2RDZ
High Resolution Crystal Structure of the Escherichia coli Cytochrome c Nitrite Reductase.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0006807 | biological_process | obsolete nitrogen compound metabolic process |
| A | 0009061 | biological_process | anaerobic respiration |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016966 | molecular_function | nitric oxide reductase activity |
| A | 0019645 | biological_process | anaerobic electron transport chain |
| A | 0020037 | molecular_function | heme binding |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0042128 | biological_process | nitrate assimilation |
| A | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006807 | biological_process | obsolete nitrogen compound metabolic process |
| B | 0009061 | biological_process | anaerobic respiration |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016966 | molecular_function | nitric oxide reductase activity |
| B | 0019645 | biological_process | anaerobic electron transport chain |
| B | 0020037 | molecular_function | heme binding |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0042128 | biological_process | nitrate assimilation |
| B | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0006807 | biological_process | obsolete nitrogen compound metabolic process |
| C | 0009061 | biological_process | anaerobic respiration |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016966 | molecular_function | nitric oxide reductase activity |
| C | 0019645 | biological_process | anaerobic electron transport chain |
| C | 0020037 | molecular_function | heme binding |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| C | 0042128 | biological_process | nitrate assimilation |
| C | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0006807 | biological_process | obsolete nitrogen compound metabolic process |
| D | 0009061 | biological_process | anaerobic respiration |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016966 | molecular_function | nitric oxide reductase activity |
| D | 0019645 | biological_process | anaerobic electron transport chain |
| D | 0020037 | molecular_function | heme binding |
| D | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| D | 0042128 | biological_process | nitrate assimilation |
| D | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A1501 |
| Chain | Residue |
| A | GLU215 |
| A | TYR216 |
| A | LYS261 |
| A | GLN263 |
| A | HOH489 |
| A | HOH499 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A1502 |
| Chain | Residue |
| A | HOH623 |
| A | HOH650 |
| A | HOH908 |
| A | HOH936 |
| A | HEC3 |
| A | HEC4 |
| A | PRO91 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEC A 1 |
| Chain | Residue |
| A | HEC3 |
| A | TYR88 |
| A | ASN89 |
| A | ASP100 |
| A | THR104 |
| A | ARG106 |
| A | CYS122 |
| A | CYS125 |
| A | LYS126 |
| A | CYS212 |
| A | HIS213 |
| A | TYR216 |
| A | PHE218 |
| A | HIS264 |
| A | HIS388 |
| A | HOH483 |
| A | HOH484 |
| A | HOH487 |
| A | HOH494 |
| A | HOH501 |
| A | HOH529 |
| A | HOH541 |
| A | HOH563 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEC A 2 |
| Chain | Residue |
| A | HEC3 |
| A | HIS49 |
| A | GLN52 |
| A | TYR53 |
| A | TRP56 |
| A | GLY159 |
| A | CYS160 |
| A | CYS163 |
| A | HIS164 |
| A | PHE171 |
| A | GLY174 |
| A | ARG201 |
| A | GLN205 |
| A | ILE283 |
| A | LYS289 |
| A | TYR298 |
| A | THR299 |
| A | HIS301 |
| A | HOH552 |
| A | HOH576 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEC A 3 |
| Chain | Residue |
| A | HEC1 |
| A | HEC2 |
| A | HEC4 |
| A | GLN62 |
| A | PRO91 |
| A | ARG92 |
| A | GLY93 |
| A | HIS94 |
| A | PHE96 |
| A | ALA97 |
| A | ASP100 |
| A | CYS125 |
| A | LYS126 |
| A | LEU158 |
| A | VAL208 |
| A | CYS209 |
| A | CYS212 |
| A | HIS213 |
| A | ILE283 |
| A | HIS286 |
| A | MET287 |
| A | ILE303 |
| A | HOH498 |
| A | HOH623 |
| A | HOH747 |
| A | CA1502 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEC A 4 |
| Chain | Residue |
| A | MET392 |
| A | HIS393 |
| A | HOH606 |
| A | HOH650 |
| A | HOH731 |
| A | HOH787 |
| A | HOH873 |
| A | CA1502 |
| A | HEC3 |
| A | HEC5 |
| A | HIS213 |
| A | GLU266 |
| A | TRP270 |
| A | HIS275 |
| A | VAL280 |
| A | THR281 |
| A | CYS282 |
| A | CYS285 |
| A | HIS286 |
| A | ASN305 |
| A | PRO306 |
| A | PHE307 |
| A | VAL329 |
| A | HIS388 |
| A | HIS391 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEC A 5 |
| Chain | Residue |
| A | HEC4 |
| A | EDO11 |
| A | ILE274 |
| A | HIS275 |
| A | ASN278 |
| A | PHE307 |
| A | THR313 |
| A | CYS314 |
| A | CYS317 |
| A | HIS318 |
| A | ARG332 |
| A | MET392 |
| A | HOH503 |
| A | HOH525 |
| B | HEC5 |
| B | HIS318 |
| B | GLN320 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A2001 |
| Chain | Residue |
| A | PHE307 |
| A | ASP308 |
| A | ASN309 |
| A | PHE310 |
| A | ALA311 |
| A | LYS322 |
| A | HOH815 |
| A | HOH981 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 481 |
| Chain | Residue |
| A | MET233 |
| A | LYS234 |
| A | VAL235 |
| A | GLU397 |
| A | MET401 |
| A | HOH523 |
| A | HOH950 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 11 |
| Chain | Residue |
| A | HEC5 |
| A | ILE274 |
| A | ARG332 |
| A | GLU396 |
| A | HOH525 |
| B | HEC5 |
| B | ARG332 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 13 |
| Chain | Residue |
| A | ASP72 |
| A | ASN337 |
| A | LYS340 |
| A | ILE341 |
| A | HOH943 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 14 |
| Chain | Residue |
| A | ASN165 |
| A | GLU177 |
| A | LEU178 |
| A | THR179 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 15 |
| Chain | Residue |
| A | HIS286 |
| A | LYS302 |
| A | GLY304 |
| A | ASN305 |
| A | ASN309 |
| A | HOH585 |
| A | HOH812 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 20 |
| Chain | Residue |
| A | ASP411 |
| A | THR414 |
| A | LYS415 |
| A | ARG418 |
| A | HOH645 |
| B | ARG413 |
| B | HOH580 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 21 |
| Chain | Residue |
| A | GLY81 |
| A | TYR82 |
| A | PRO83 |
| A | ARG86 |
| A | HOH1025 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 22 |
| Chain | Residue |
| A | ASP345 |
| A | VAL348 |
| A | ILE431 |
| A | HOH635 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B1501 |
| Chain | Residue |
| B | GLU215 |
| B | TYR216 |
| B | LYS261 |
| B | GLN263 |
| B | HOH504 |
| B | HOH528 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B1502 |
| Chain | Residue |
| B | HEC3 |
| B | HEC4 |
| B | PRO91 |
| B | HOH661 |
| B | HOH676 |
| B | HOH716 |
| B | HOH955 |
| site_id | CC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEC B 1 |
| Chain | Residue |
| B | HEC3 |
| B | TYR88 |
| B | ASN89 |
| B | PRO91 |
| B | ASP100 |
| B | THR104 |
| B | ARG106 |
| B | THR107 |
| B | LEU118 |
| B | CYS122 |
| B | CYS125 |
| B | LYS126 |
| B | CYS212 |
| B | HIS213 |
| B | TYR216 |
| B | VAL225 |
| B | HIS264 |
| B | HIS388 |
| B | HOH484 |
| B | HOH485 |
| B | HOH490 |
| B | HOH493 |
| B | HOH517 |
| B | HOH522 |
| B | HOH534 |
| B | HOH545 |
| B | HOH1025 |
| site_id | CC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEC B 2 |
| Chain | Residue |
| B | HEC3 |
| B | HIS49 |
| B | GLN52 |
| B | TYR53 |
| B | TRP56 |
| B | GLY159 |
| B | CYS160 |
| B | CYS163 |
| B | HIS164 |
| B | PHE171 |
| B | GLY174 |
| B | ARG201 |
| B | GLN205 |
| B | ILE283 |
| B | MET287 |
| B | LYS289 |
| B | TYR298 |
| B | THR299 |
| B | HIS301 |
| B | HOH527 |
| B | HOH546 |
| site_id | CC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEC B 3 |
| Chain | Residue |
| B | HEC1 |
| B | HEC2 |
| B | HEC4 |
| B | GLN62 |
| B | PRO91 |
| B | ARG92 |
| B | GLY93 |
| B | HIS94 |
| B | PHE96 |
| B | ALA97 |
| B | ASP100 |
| B | CYS125 |
| B | LEU158 |
| B | VAL208 |
| B | CYS209 |
| B | CYS212 |
| B | HIS213 |
| B | HIS286 |
| B | MET287 |
| B | ILE303 |
| B | HOH661 |
| B | HOH720 |
| B | CA1502 |
| site_id | CC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEC B 4 |
| Chain | Residue |
| B | HEC3 |
| B | HEC5 |
| B | HIS213 |
| B | GLU266 |
| B | TRP270 |
| B | HIS275 |
| B | VAL280 |
| B | THR281 |
| B | CYS282 |
| B | CYS285 |
| B | HIS286 |
| B | ASN305 |
| B | PRO306 |
| B | PHE307 |
| B | VAL329 |
| B | HIS388 |
| B | HIS391 |
| B | MET392 |
| B | HIS393 |
| B | HOH676 |
| B | HOH686 |
| B | HOH692 |
| B | CA1502 |
| site_id | CC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEC B 5 |
| Chain | Residue |
| A | HEC5 |
| A | EDO11 |
| A | HIS318 |
| A | GLN320 |
| B | HEC4 |
| B | ILE274 |
| B | HIS275 |
| B | VAL280 |
| B | PRO306 |
| B | PHE307 |
| B | THR313 |
| B | CYS314 |
| B | CYS317 |
| B | HIS318 |
| B | ARG332 |
| B | MET392 |
| B | HOH506 |
| B | HOH509 |
| B | HOH568 |
| B | HOH701 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B2001 |
| Chain | Residue |
| B | PHE307 |
| B | ASP308 |
| B | ASN309 |
| B | PHE310 |
| B | ALA311 |
| B | LYS322 |
| B | HOH804 |
| B | HOH917 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 481 |
| Chain | Residue |
| B | MET233 |
| B | LYS234 |
| B | VAL235 |
| B | GLU268 |
| B | GLU397 |
| B | MET401 |
| B | HOH558 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 16 |
| Chain | Residue |
| A | ARG413 |
| A | HOH559 |
| B | ASP411 |
| B | THR414 |
| B | LYS415 |
| B | ARG418 |
| B | HOH813 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 17 |
| Chain | Residue |
| B | ASP407 |
| B | LYS408 |
| B | ASP411 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 18 |
| Chain | Residue |
| B | CYS285 |
| B | HIS286 |
| B | LYS302 |
| B | GLY304 |
| B | ASN305 |
| B | PRO306 |
| B | HOH697 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 19 |
| Chain | Residue |
| B | MET120 |
| B | ASP137 |
| B | GLY141 |
| B | TYR142 |
| B | HIS144 |
| B | ARG149 |
| B | HOH499 |
| site_id | DC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 20 |
| Chain | Residue |
| B | ASP345 |
| B | VAL348 |
| B | ILE434 |
| B | HOH643 |
| B | HOH934 |
| B | HOH954 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C1501 |
| Chain | Residue |
| C | GLU215 |
| C | TYR216 |
| C | LYS261 |
| C | GLN263 |
| C | HOH495 |
| C | HOH514 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C1502 |
| Chain | Residue |
| C | HEC3 |
| C | HEC4 |
| C | PRO91 |
| C | HOH609 |
| C | HOH712 |
| C | HOH769 |
| site_id | DC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEC C 1 |
| Chain | Residue |
| C | HEC3 |
| C | TYR88 |
| C | ASN89 |
| C | ASP100 |
| C | THR104 |
| C | ARG106 |
| C | LEU118 |
| C | CYS122 |
| C | CYS125 |
| C | LYS126 |
| C | CYS212 |
| C | HIS213 |
| C | TYR216 |
| C | PHE218 |
| C | VAL225 |
| C | HIS264 |
| C | HIS388 |
| C | HOH486 |
| C | HOH491 |
| C | HOH505 |
| C | HOH507 |
| C | HOH517 |
| C | HOH518 |
| C | HOH522 |
| C | HOH558 |
| site_id | DC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEC C 2 |
| Chain | Residue |
| C | HEC3 |
| C | HIS49 |
| C | GLN52 |
| C | TYR53 |
| C | TRP56 |
| C | GLY159 |
| C | CYS160 |
| C | CYS163 |
| C | HIS164 |
| C | PHE171 |
| C | GLY174 |
| C | PRO176 |
| C | ARG201 |
| C | GLN205 |
| C | ILE283 |
| C | LYS289 |
| C | TYR298 |
| C | THR299 |
| C | HIS301 |
| C | HOH542 |
| C | HOH630 |
| site_id | DC8 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEC C 3 |
| Chain | Residue |
| C | HEC1 |
| C | HEC2 |
| C | HEC4 |
| C | GLN62 |
| C | PRO91 |
| C | ARG92 |
| C | GLY93 |
| C | HIS94 |
| C | PHE96 |
| C | ALA97 |
| C | ASP100 |
| C | CYS125 |
| C | LEU158 |
| C | VAL208 |
| C | CYS209 |
| C | CYS212 |
| C | HIS213 |
| C | HIS286 |
| C | MET287 |
| C | ILE303 |
| C | HOH640 |
| C | HOH712 |
| C | CA1502 |
| site_id | DC9 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEC C 4 |
| Chain | Residue |
| C | HEC3 |
| C | HEC5 |
| C | HIS213 |
| C | GLU266 |
| C | TRP270 |
| C | HIS275 |
| C | VAL280 |
| C | THR281 |
| C | CYS282 |
| C | CYS285 |
| C | HIS286 |
| C | ASN305 |
| C | PRO306 |
| C | VAL329 |
| C | HIS388 |
| C | HIS391 |
| C | MET392 |
| C | HIS393 |
| C | HOH578 |
| C | HOH660 |
| C | HOH674 |
| C | HOH769 |
| C | HOH884 |
| C | HOH963 |
| C | CA1502 |
| site_id | EC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEC C 5 |
| Chain | Residue |
| C | HEC4 |
| C | EDO12 |
| C | ILE274 |
| C | HIS275 |
| C | VAL280 |
| C | ASP284 |
| C | PHE307 |
| C | THR313 |
| C | CYS314 |
| C | CYS317 |
| C | HIS318 |
| C | ARG332 |
| C | MET392 |
| C | HOH493 |
| C | HOH500 |
| D | HEC5 |
| D | HIS318 |
| D | GLN320 |
| site_id | EC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C2001 |
| Chain | Residue |
| C | PHE307 |
| C | ASP308 |
| C | ASN309 |
| C | PHE310 |
| C | ALA311 |
| C | LYS322 |
| site_id | EC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 481 |
| Chain | Residue |
| C | MET233 |
| C | LYS234 |
| C | VAL235 |
| C | GLU268 |
| C | GLU397 |
| C | HOH508 |
| site_id | EC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 12 |
| Chain | Residue |
| C | HEC5 |
| C | ILE274 |
| C | ARG332 |
| D | HEC5 |
| D | ILE274 |
| D | ARG332 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 21 |
| Chain | Residue |
| C | ASP407 |
| C | LYS408 |
| C | ASP411 |
| C | HOH889 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 22 |
| Chain | Residue |
| C | ASP411 |
| C | LYS415 |
| C | ARG418 |
| C | HOH681 |
| D | ARG413 |
| D | HOH639 |
| site_id | EC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 23 |
| Chain | Residue |
| C | CYS285 |
| C | HIS286 |
| C | LYS302 |
| C | GLY304 |
| C | ASN305 |
| C | PRO306 |
| C | ASN309 |
| C | HOH759 |
| site_id | EC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 25 |
| Chain | Residue |
| C | ASP345 |
| C | ILE431 |
| C | ILE434 |
| C | HOH529 |
| C | HOH689 |
| C | HOH807 |
| site_id | EC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D1501 |
| Chain | Residue |
| D | GLU215 |
| D | TYR216 |
| D | LYS261 |
| D | GLN263 |
| D | HOH497 |
| D | HOH520 |
| site_id | FC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D1502 |
| Chain | Residue |
| D | HEC3 |
| D | HEC4 |
| D | PRO91 |
| D | HOH707 |
| D | HOH758 |
| site_id | FC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEC D 1 |
| Chain | Residue |
| D | HEC3 |
| D | TYR88 |
| D | ASN89 |
| D | PRO91 |
| D | ASP100 |
| D | THR104 |
| D | ARG106 |
| D | LEU118 |
| D | CYS122 |
| D | CYS125 |
| D | LYS126 |
| D | CYS212 |
| D | HIS213 |
| D | TYR216 |
| D | VAL225 |
| D | HIS264 |
| D | HIS388 |
| D | HOH487 |
| D | HOH489 |
| D | HOH490 |
| D | HOH492 |
| D | HOH511 |
| D | HOH523 |
| D | HOH529 |
| D | HOH542 |
| D | HOH555 |
| site_id | FC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEC D 2 |
| Chain | Residue |
| D | HEC3 |
| D | HIS49 |
| D | GLN52 |
| D | TYR53 |
| D | TRP56 |
| D | GLY159 |
| D | CYS160 |
| D | CYS163 |
| D | HIS164 |
| D | PHE171 |
| D | GLY174 |
| D | ARG201 |
| D | GLN205 |
| D | ILE283 |
| D | MET287 |
| D | LYS289 |
| D | TYR298 |
| D | THR299 |
| D | HIS301 |
| D | HOH585 |
| D | HOH612 |
| site_id | FC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEC D 3 |
| Chain | Residue |
| D | HEC1 |
| D | HEC2 |
| D | HEC4 |
| D | GLN62 |
| D | PRO91 |
| D | ARG92 |
| D | GLY93 |
| D | HIS94 |
| D | PHE96 |
| D | ALA97 |
| D | ASP100 |
| D | CYS125 |
| D | LYS126 |
| D | LEU158 |
| D | VAL208 |
| D | CYS209 |
| D | CYS212 |
| D | HIS213 |
| D | HIS286 |
| D | MET287 |
| D | ILE303 |
| D | HOH522 |
| D | HOH707 |
| D | HOH776 |
| D | CA1502 |
| site_id | FC5 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEC D 4 |
| Chain | Residue |
| D | HEC3 |
| D | HEC5 |
| D | HIS213 |
| D | GLU266 |
| D | TRP270 |
| D | HIS275 |
| D | VAL280 |
| D | THR281 |
| D | CYS282 |
| D | CYS285 |
| D | HIS286 |
| D | ASN305 |
| D | PRO306 |
| D | VAL329 |
| D | HIS391 |
| D | MET392 |
| D | HIS393 |
| D | HOH604 |
| D | HOH659 |
| D | HOH681 |
| D | HOH700 |
| D | HOH709 |
| D | HOH738 |
| D | HOH779 |
| D | CA1502 |
| site_id | FC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEC D 5 |
| Chain | Residue |
| C | HEC5 |
| C | EDO12 |
| C | HIS318 |
| C | GLN320 |
| D | HEC4 |
| D | ILE274 |
| D | HIS275 |
| D | VAL280 |
| D | PRO306 |
| D | PHE307 |
| D | THR313 |
| D | CYS314 |
| D | CYS317 |
| D | HIS318 |
| D | ARG332 |
| D | MET392 |
| D | HOH525 |
| D | HOH550 |
| D | HOH567 |
| D | HOH667 |
| site_id | FC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D2001 |
| Chain | Residue |
| D | PHE307 |
| D | ASP308 |
| D | ASN309 |
| D | PHE310 |
| D | ALA311 |
| D | LYS322 |
| site_id | FC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 481 |
| Chain | Residue |
| D | ARG65 |
| D | ASN89 |
| D | ARG92 |
| D | ASP100 |
| D | HOH614 |
| D | HOH1029 |
| site_id | FC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 482 |
| Chain | Residue |
| C | ARG413 |
| C | HOH554 |
| C | HOH622 |
| D | THR414 |
| D | LYS415 |
| D | ARG418 |
| site_id | GC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 6 |
| Chain | Residue |
| D | MET233 |
| D | LYS234 |
| D | VAL235 |
| D | GLU268 |
| D | GLU397 |
| D | HOH623 |
| D | HOH1011 |
| site_id | GC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 21 |
| Chain | Residue |
| D | SER55 |
| D | TYR298 |
| D | ASP300 |
| D | LYS302 |
| D | HOH689 |
| D | HOH928 |
| D | HOH995 |
| site_id | GC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 22 |
| Chain | Residue |
| D | GLY81 |
| D | TYR82 |
| D | PRO83 |
| D | ARG86 |
| D | LEU446 |
| D | HOH528 |
| D | HOH642 |
| site_id | GC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 23 |
| Chain | Residue |
| D | ASP345 |
| D | VAL348 |
| D | HIS349 |
| D | HOH730 |
| site_id | GC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 24 |
| Chain | Residue |
| D | MET120 |
| D | ASP137 |
| D | GLY141 |
| D | TYR142 |
| D | HIS144 |
| D | ARG149 |
| D | HOH512 |
| site_id | GC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO D 25 |
| Chain | Residue |
| A | THR436 |
| A | HOH753 |
| C | HOH646 |
| D | GLU236 |
| D | GLU239 |
| D | ARG380 |
| D | HOH510 |
| D | HOH649 |
| D | HOH1035 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | BINDING: axial binding residue => ECO:0007744|PDB:1GU6, ECO:0007744|PDB:2RDZ, ECO:0007744|PDB:2RF7, ECO:0007744|PDB:3L1T, ECO:0007744|PDB:3TOR |
| Chain | Residue | Details |
| A | HIS94 | |
| A | HIS393 | |
| B | HIS94 | |
| B | LYS126 | |
| B | HIS164 | |
| B | HIS213 | |
| B | HIS275 | |
| B | HIS286 | |
| B | HIS301 | |
| B | HIS318 | |
| B | HIS393 | |
| C | HIS94 | |
| C | LYS126 | |
| C | HIS164 | |
| C | HIS213 | |
| C | HIS275 | |
| C | HIS286 | |
| C | HIS301 | |
| C | HIS318 | |
| C | HIS393 | |
| D | HIS94 | |
| D | LYS126 | |
| D | HIS164 | |
| D | HIS213 | |
| D | HIS275 | |
| D | HIS286 | |
| D | HIS301 | |
| D | HIS318 | |
| D | HIS393 | |
| A | LYS126 | |
| A | HIS164 | |
| A | HIS213 | |
| A | HIS275 | |
| A | HIS286 | |
| A | HIS301 | |
| A | HIS318 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | BINDING: covalent => ECO:0007744|PDB:1GU6, ECO:0007744|PDB:2RDZ, ECO:0007744|PDB:2RF7, ECO:0007744|PDB:3L1T, ECO:0007744|PDB:3TOR |
| Chain | Residue | Details |
| A | CYS209 | |
| A | CYS212 | |
| A | CYS282 | |
| A | CYS314 | |
| B | CYS122 | |
| B | CYS125 | |
| B | CYS160 | |
| B | CYS163 | |
| B | CYS209 | |
| B | CYS212 | |
| B | CYS282 | |
| B | CYS314 | |
| C | CYS122 | |
| C | CYS125 | |
| C | CYS160 | |
| C | CYS163 | |
| C | CYS209 | |
| C | CYS212 | |
| C | CYS282 | |
| C | CYS314 | |
| D | CYS122 | |
| D | CYS125 | |
| D | CYS160 | |
| D | CYS163 | |
| D | CYS209 | |
| D | CYS212 | |
| D | CYS282 | |
| D | CYS314 | |
| A | CYS122 | |
| A | CYS125 | |
| A | CYS160 | |
| A | CYS163 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0007744|PDB:1GU6, ECO:0007744|PDB:2RDZ, ECO:0007744|PDB:2RF7, ECO:0007744|PDB:3L1T, ECO:0007744|PDB:3TOR |
| Chain | Residue | Details |
| A | GLU215 | |
| A | LYS261 | |
| B | GLU215 | |
| B | LYS261 | |
| C | GLU215 | |
| C | LYS261 | |
| D | GLU215 | |
| D | LYS261 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| C | TYR216 | |
| C | HIS264 | |
| D | TYR216 | |
| D | HIS264 | |
| A | TYR216 | |
| A | HIS264 | |
| B | TYR216 | |
| B | HIS264 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0007744|PDB:1GU6, ECO:0007744|PDB:2RDZ, ECO:0007744|PDB:3L1T, ECO:0007744|PDB:3TOR |
| Chain | Residue | Details |
| A | GLN263 | |
| B | GLN263 | |
| C | GLN263 | |
| D | GLN263 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | BINDING: covalent => ECO:0007744|PDB:1GU6, ECO:0007744|PDB:2RDZ, ECO:0007744|PDB:2RF7 |
| Chain | Residue | Details |
| C | CYS285 | |
| C | CYS317 | |
| D | CYS285 | |
| D | CYS317 | |
| A | CYS285 | |
| A | CYS317 | |
| B | CYS285 | |
| B | CYS317 |
