2R94

Crystal Structure of KD(P)GA from T.tenax

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0008675	molecular_function	2-dehydro-3-deoxy-phosphogluconate aldolase activity
A	0008700	molecular_function	4-hydroxy-2-oxoglutarate aldolase activity
A	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
A	0009436	biological_process	glyoxylate catabolic process
A	0016829	molecular_function	lyase activity
A	0061677	molecular_function	2-dehydro-3-deoxy-D-gluconate aldolase activity
B	0005829	cellular_component	cytosol
B	0008675	molecular_function	2-dehydro-3-deoxy-phosphogluconate aldolase activity
B	0008700	molecular_function	4-hydroxy-2-oxoglutarate aldolase activity
B	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
B	0009436	biological_process	glyoxylate catabolic process
B	0016829	molecular_function	lyase activity
B	0061677	molecular_function	2-dehydro-3-deoxy-D-gluconate aldolase activity
C	0005829	cellular_component	cytosol
C	0008675	molecular_function	2-dehydro-3-deoxy-phosphogluconate aldolase activity
C	0008700	molecular_function	4-hydroxy-2-oxoglutarate aldolase activity
C	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
C	0009436	biological_process	glyoxylate catabolic process
C	0016829	molecular_function	lyase activity
C	0061677	molecular_function	2-dehydro-3-deoxy-D-gluconate aldolase activity
D	0005829	cellular_component	cytosol
D	0008675	molecular_function	2-dehydro-3-deoxy-phosphogluconate aldolase activity
D	0008700	molecular_function	4-hydroxy-2-oxoglutarate aldolase activity
D	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
D	0009436	biological_process	glyoxylate catabolic process
D	0016829	molecular_function	lyase activity
D	0061677	molecular_function	2-dehydro-3-deoxy-D-gluconate aldolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PYR A 999

Chain	Residue
A	PRO26
A	PHE57
A	GLY60
A	THR61
A	THR62
A	TYR148
A	LYS173
A	GLY197

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PYR D 999

Chain	Residue
D	PHE57
D	GLY60
D	THR61
D	THR62
D	TYR148
D	LYS173
D	HOH1059
D	PRO26

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PYR B 999

Chain	Residue
B	PRO26
B	PHE57
B	GLY60
B	THR61
B	THR62
B	TYR148
B	LYS173

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PYR C 999

Chain	Residue
C	PRO26
C	PHE57
C	GLY60
C	THR61
C	THR62
C	TYR148
C	LYS173

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000269|PubMed:18186475

Chain	Residue	Details
A	LYS173
D	LYS173
B	LYS173
C	LYS173

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING:

Chain	Residue	Details
B	THR61
B	LYS173
C	THR61
C	LYS173
A	THR61
A	LYS173
D	THR61
D	LYS173

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	TYR148
D	TYR148
B	TYR148
C	TYR148

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Proton shuttle

Chain	Residue	Details
A	TYR148
D	TYR148
B	TYR148
C	TYR148

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