2QYO
Crystal structure of isoflavone O-methyltransferase homolog in complex with biochanin A and SAH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0019438 | biological_process | obsolete aromatic compound biosynthetic process |
| A | 0032259 | biological_process | methylation |
| A | 0033800 | molecular_function | isoflavone 7-O-methyltransferase activity |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008171 | molecular_function | O-methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0019438 | biological_process | obsolete aromatic compound biosynthetic process |
| B | 0032259 | biological_process | methylation |
| B | 0033800 | molecular_function | isoflavone 7-O-methyltransferase activity |
| B | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K A 358 |
| Chain | Residue |
| A | HIS262 |
| A | ASP293 |
| A | GLU323 |
| A | HOH703 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K A 362 |
| Chain | Residue |
| A | THR145 |
| A | LEU155 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K B 358 |
| Chain | Residue |
| B | GLU298 |
| B | HOH782 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K B 360 |
| Chain | Residue |
| B | ASP293 |
| B | GLU323 |
| B | HOH703 |
| B | HIS262 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SAH A 601 |
| Chain | Residue |
| A | GLY201 |
| A | THR207 |
| A | ASP224 |
| A | ARG225 |
| A | ASP244 |
| A | MET245 |
| A | PHE246 |
| A | LYS258 |
| A | ALA259 |
| A | TRP264 |
| A | HOH717 |
| A | HOH719 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE QSO A 701 |
| Chain | Residue |
| A | LEU128 |
| A | SER129 |
| A | PHE132 |
| A | TYR165 |
| A | HIS262 |
| A | ASP263 |
| A | ILE316 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SAH B 602 |
| Chain | Residue |
| B | GLY201 |
| B | THR207 |
| B | ASP224 |
| B | ARG225 |
| B | ASP244 |
| B | MET245 |
| B | PHE246 |
| B | LYS258 |
| B | TRP264 |
| B | HOH707 |
| B | HOH735 |
| B | HOH755 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE QSO B 701 |
| Chain | Residue |
| A | TYR25 |
| B | LEU128 |
| B | SER129 |
| B | PHE132 |
| B | HIS262 |
