2QLV

Crystal structure of the heterotrimer core of the S. cerevisiae AMPK homolog SNF1

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000166	molecular_function	nucleotide binding
C	0004679	molecular_function	AMP-activated protein kinase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005641	cellular_component	nuclear envelope lumen
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006914	biological_process	autophagy
C	0007031	biological_process	peroxisome organization
C	0016208	molecular_function	AMP binding
C	0019887	molecular_function	protein kinase regulator activity
C	0019901	molecular_function	protein kinase binding
C	0030447	biological_process	filamentous growth
C	0031588	cellular_component	nucleotide-activated protein kinase complex
C	0042802	molecular_function	identical protein binding
C	0043539	molecular_function	protein serine/threonine kinase activator activity
C	0045722	biological_process	positive regulation of gluconeogenesis
C	1904547	biological_process	regulation of cellular response to glucose starvation
C	2000217	biological_process	regulation of invasive growth in response to glucose limitation
F	0000166	molecular_function	nucleotide binding
F	0004679	molecular_function	AMP-activated protein kinase activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005641	cellular_component	nuclear envelope lumen
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0006914	biological_process	autophagy
F	0007031	biological_process	peroxisome organization
F	0016208	molecular_function	AMP binding
F	0019887	molecular_function	protein kinase regulator activity
F	0019901	molecular_function	protein kinase binding
F	0030447	biological_process	filamentous growth
F	0031588	cellular_component	nucleotide-activated protein kinase complex
F	0042802	molecular_function	identical protein binding
F	0043539	molecular_function	protein serine/threonine kinase activator activity
F	0045722	biological_process	positive regulation of gluconeogenesis
F	1904547	biological_process	regulation of cellular response to glucose starvation
F	2000217	biological_process	regulation of invasive growth in response to glucose limitation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q10343

Chain	Residue	Details
C	ILE42
C	ARG146
C	THR166
C	ARG291
F	ILE42
F	ARG146
F	THR166
F	ARG291

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:22019086, ECO:0007744|PDB:3T4N

Chain	Residue	Details
C	THR195
C	LYS200
C	SER221
C	THR309
F	THR195
F	LYS200
F	SER221
F	THR309

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site_id	SWS_FT_FI3
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:24108357

Chain	Residue	Details
A	LYS549
D	LYS549

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