2Q6G

Crystal structure of SARS-CoV main protease H41A mutant in complex with an N-terminal substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008233	molecular_function	peptidase activity
A	0019082	biological_process	viral protein processing
B	0008233	molecular_function	peptidase activity
B	0019082	biological_process	viral protein processing

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Cleavage; by 3CL-PRO => ECO:0000269|PubMed:14561748

Chain	Residue	Details
C	GLN6
D	GLN6
B	ALA41
B	CYS145

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Cleavage; by 3CL-PRO => ECO:0000269|PubMed:14561748

Chain	Residue	Details
A	GLN306
B	GLN306

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues
Details	M-CSA 830

Chain	Residue	Details
A	ALA41	proton acceptor, proton donor
A	GLY143	electrostatic stabiliser
A	CYS145	electrostatic stabiliser

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site_id	MCSA2
Number of Residues
Details	M-CSA 830

Chain	Residue	Details
B	ALA41	proton acceptor, proton donor
B	GLY143	electrostatic stabiliser
B	CYS145	electrostatic stabiliser

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