2PH5

Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0047296	molecular_function	homospermidine synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 502

Chain	Residue
A	HIS257
A	SER258
A	ASN259
A	ARG368

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site_id	AC2
Number of Residues	26
Details	BINDING SITE FOR RESIDUE NAD A 501

Chain	Residue
A	ALA48
A	GLU49
A	GLN66
A	GLN67
A	ILE68
A	VAL90
A	SER91
A	ILE92
A	ALA113
A	ALA114
A	GLY157
A	ALA158
A	ASN159
A	PRO160
A	VAL396
A	HOH503
A	HOH509
A	HOH510
A	HOH600
A	HOH603
A	HOH630
A	GLY20
A	PHE21
A	GLY22
A	CYS23
A	VAL24

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