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2O8A

rat PP1cgamma complexed with mouse inhibitor-2

Functional Information from GO Data
ChainGOidnamespacecontents
A0000775cellular_componentchromosome, centromeric region
A0000776cellular_componentkinetochore
A0000781cellular_componentchromosome, telomeric region
A0001824biological_processblastocyst development
A0004721molecular_functionphosphoprotein phosphatase activity
A0004722molecular_functionprotein serine/threonine phosphatase activity
A0005515molecular_functionprotein binding
A0005521molecular_functionlamin binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005694cellular_componentchromosome
A0005730cellular_componentnucleolus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005741cellular_componentmitochondrial outer membrane
A0005815cellular_componentmicrotubule organizing center
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005977biological_processglycogen metabolic process
A0006470biological_processprotein dephosphorylation
A0007283biological_processspermatogenesis
A0008157molecular_functionprotein phosphatase 1 binding
A0016607cellular_componentnuclear speck
A0016787molecular_functionhydrolase activity
A0016791molecular_functionphosphatase activity
A0017018molecular_functionmyosin phosphatase activity
A0019901molecular_functionprotein kinase binding
A0019903molecular_functionprotein phosphatase binding
A0019904molecular_functionprotein domain specific binding
A0030182biological_processneuron differentiation
A0030496cellular_componentmidbody
A0032154cellular_componentcleavage furrow
A0032922biological_processcircadian regulation of gene expression
A0032991cellular_componentprotein-containing complex
A0042752biological_processregulation of circadian rhythm
A0043153biological_processentrainment of circadian clock by photoperiod
A0043197cellular_componentdendritic spine
A0044877molecular_functionprotein-containing complex binding
A0046822biological_processregulation of nucleocytoplasmic transport
A0046872molecular_functionmetal ion binding
A0048511biological_processrhythmic process
A0051301biological_processcell division
A0060252biological_processpositive regulation of glial cell proliferation
A0072357cellular_componentPTW/PP1 phosphatase complex
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A0098978cellular_componentglutamatergic synapse
B0000775cellular_componentchromosome, centromeric region
B0000776cellular_componentkinetochore
B0000781cellular_componentchromosome, telomeric region
B0001824biological_processblastocyst development
B0004721molecular_functionphosphoprotein phosphatase activity
B0004722molecular_functionprotein serine/threonine phosphatase activity
B0005515molecular_functionprotein binding
B0005521molecular_functionlamin binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005694cellular_componentchromosome
B0005730cellular_componentnucleolus
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005741cellular_componentmitochondrial outer membrane
B0005815cellular_componentmicrotubule organizing center
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005977biological_processglycogen metabolic process
B0006470biological_processprotein dephosphorylation
B0007283biological_processspermatogenesis
B0008157molecular_functionprotein phosphatase 1 binding
B0016607cellular_componentnuclear speck
B0016787molecular_functionhydrolase activity
B0016791molecular_functionphosphatase activity
B0017018molecular_functionmyosin phosphatase activity
B0019901molecular_functionprotein kinase binding
B0019903molecular_functionprotein phosphatase binding
B0019904molecular_functionprotein domain specific binding
B0030182biological_processneuron differentiation
B0030496cellular_componentmidbody
B0032154cellular_componentcleavage furrow
B0032922biological_processcircadian regulation of gene expression
B0032991cellular_componentprotein-containing complex
B0042752biological_processregulation of circadian rhythm
B0043153biological_processentrainment of circadian clock by photoperiod
B0043197cellular_componentdendritic spine
B0044877molecular_functionprotein-containing complex binding
B0046822biological_processregulation of nucleocytoplasmic transport
B0046872molecular_functionmetal ion binding
B0048511biological_processrhythmic process
B0051301biological_processcell division
B0060252biological_processpositive regulation of glial cell proliferation
B0072357cellular_componentPTW/PP1 phosphatase complex
B0098793cellular_componentpresynapse
B0098794cellular_componentpostsynapse
B0098978cellular_componentglutamatergic synapse
I0004864molecular_functionprotein phosphatase inhibitor activity
I0005977biological_processglycogen metabolic process
I0009966biological_processregulation of signal transduction
I0019904molecular_functionprotein domain specific binding
I0030426cellular_componentgrowth cone
I0043197cellular_componentdendritic spine
I0043666biological_processregulation of phosphoprotein phosphatase activity
I0140678molecular_functionmolecular function inhibitor activity
J0004864molecular_functionprotein phosphatase inhibitor activity
J0005977biological_processglycogen metabolic process
J0009966biological_processregulation of signal transduction
J0019904molecular_functionprotein domain specific binding
J0030426cellular_componentgrowth cone
J0043197cellular_componentdendritic spine
J0043666biological_processregulation of phosphoprotein phosphatase activity
J0140678molecular_functionmolecular function inhibitor activity
Functional Information from PROSITE/UniProt
site_idPS00125
Number of Residues6
DetailsSER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE
ChainResidueDetails
ALEU121-GLU126

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P11845
ChainResidueDetails
IALA3
JALA3

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine; by ATM => ECO:0000250|UniProtKB:P41236
ChainResidueDetails
IGLN46
JGLN46
BASP64
BHIS66

site_idSWS_FT_FI3
Number of Residues6
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:21183079
ChainResidueDetails
IPRO75
IPRO98
IARG118
JPRO75
JPRO98
JARG118
BHIS173
BHIS248

site_idSWS_FT_FI4
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079
ChainResidueDetails
IASP89
IGLU91
IPRO132
JASP89
JGLU91
JPRO132

site_idSWS_FT_FI5
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17242355, ECO:0007744|PubMed:19131326, ECO:0007744|PubMed:21183079
ChainResidueDetails
ISER123
IGLY124
JSER123
JGLY124

220113

PDB entries from 2024-05-22

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