Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 402 |
| Chain | Residue |
| B | THR74 |
| B | ASN88 |
| B | HOH446 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 403 |
| Chain | Residue |
| B | TRP6 |
| B | GOL407 |
| B | HOH488 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 404 |
| Chain | Residue |
| B | HOH486 |
| B | HOH513 |
| B | THR4 |
| B | TRP6 |
| B | LYS7 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 405 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH463 |
| B | ARG41 |
| site_id | AC5 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE AB1 A 400 |
| Chain | Residue |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | VAL32 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH412 |
| A | HOH417 |
| A | HOH419 |
| A | HOH452 |
| A | HOH549 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | VAL32 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | PRO81 |
| B | VAL82 |
| B | HOH410 |
| B | HOH457 |
| B | HOH461 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 406 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | SER37 |
| B | THR12 |
| B | GLU65 |
| B | CYS67 |
| B | GLY68 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 407 |
| Chain | Residue |
| A | HOH455 |
| B | LYS55 |
| B | ARG57 |
| B | CL403 |
| B | HOH549 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR26 | |
| B | THR26 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PRO1 | |
| B | PRO1 | |
