2INR
Crystal structure of a 59 kDa fragment of topoisomerase IV subunit A (GrlA) from Staphylococcus aureus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005694 | cellular_component | chromosome |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006265 | biological_process | DNA topological change |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: O-(5'-phospho-DNA)-tyrosine intermediate => ECO:0000255|HAMAP-Rule:MF_00937 |
| Chain | Residue | Details |
| A | TYR119 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | SITE: Interaction with DNA => ECO:0000255|HAMAP-Rule:MF_00937 |
| Chain | Residue | Details |
| A | LYS39 | |
| A | HIS75 | |
| A | HIS77 | |
| A | ARG88 | |
| A | LYS94 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00937 |
| Chain | Residue | Details |
| A | ARG118 |
