2IMI
Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0006749 | biological_process | glutathione metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0006749 | biological_process | glutathione metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE GSH A 224 |
| Chain | Residue |
| A | SER12 |
| A | SER68 |
| A | PHE108 |
| A | ARG112 |
| A | HOH229 |
| A | HOH250 |
| A | HOH259 |
| A | HOH291 |
| A | HOH357 |
| A | HOH366 |
| A | HOH392 |
| A | PRO14 |
| A | HOH422 |
| A | LEU36 |
| A | HIS41 |
| A | HIS53 |
| A | THR54 |
| A | ILE55 |
| A | PRO56 |
| A | GLU67 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GSH B 226 |
| Chain | Residue |
| B | SER12 |
| B | PRO14 |
| B | LEU36 |
| B | HIS41 |
| B | HIS53 |
| B | THR54 |
| B | ILE55 |
| B | PRO56 |
| B | GLU67 |
| B | SER68 |
| B | PHE108 |
| B | ARG112 |
| B | HOH236 |
| B | HOH239 |
| B | HOH303 |
| B | HOH307 |
| B | HOH347 |
| B | HOH412 |
