2IGK
Crystal structure of recombinant pyranose 2-oxidase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0050233 | molecular_function | pyranose oxidase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0050233 | molecular_function | pyranose oxidase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0050233 | molecular_function | pyranose oxidase activity |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0050233 | molecular_function | pyranose oxidase activity |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| E | 0042597 | cellular_component | periplasmic space |
| E | 0050233 | molecular_function | pyranose oxidase activity |
| E | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| F | 0042597 | cellular_component | periplasmic space |
| F | 0050233 | molecular_function | pyranose oxidase activity |
| F | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| G | 0042597 | cellular_component | periplasmic space |
| G | 0050233 | molecular_function | pyranose oxidase activity |
| G | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| H | 0042597 | cellular_component | periplasmic space |
| H | 0050233 | molecular_function | pyranose oxidase activity |
| H | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE FAD A 801 |
| Chain | Residue |
| A | GLY53 |
| A | GLY163 |
| A | MET164 |
| A | HIS167 |
| A | TRP168 |
| A | THR169 |
| A | CYS170 |
| A | ALA171 |
| A | VAL281 |
| A | CYS283 |
| A | THR319 |
| A | GLY55 |
| A | ALA320 |
| A | HIS324 |
| A | LEU547 |
| A | ASN593 |
| A | THR595 |
| A | HOH1033 |
| A | HOH1043 |
| A | HOH1142 |
| A | HOH1162 |
| A | HOH1287 |
| A | PRO56 |
| A | HOH1503 |
| A | HOH1536 |
| A | HOH2632 |
| A | HOH2954 |
| A | HOH3708 |
| A | ILE57 |
| A | ASP76 |
| A | ILE77 |
| A | THR158 |
| A | ARG159 |
| A | VAL160 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MES B 901 |
| Chain | Residue |
| A | SER462 |
| A | ILE463 |
| A | ASP464 |
| A | LEU467 |
| B | LEU121 |
| B | VAL123 |
| B | TRP131 |
| B | ALA133 |
| B | PHE137 |
| B | ARG139 |
| B | HOH2032 |
| B | HOH2400 |
| C | LEU149 |
| site_id | AC3 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE FAD B 801 |
| Chain | Residue |
| B | VAL52 |
| B | GLY53 |
| B | GLY55 |
| B | PRO56 |
| B | ILE57 |
| B | ASP76 |
| B | ILE77 |
| B | THR158 |
| B | ARG159 |
| B | VAL160 |
| B | GLY163 |
| B | MET164 |
| B | HIS167 |
| B | TRP168 |
| B | THR169 |
| B | CYS170 |
| B | ALA171 |
| B | VAL281 |
| B | CYS283 |
| B | THR319 |
| B | ALA320 |
| B | HIS324 |
| B | LEU547 |
| B | ASN593 |
| B | THR595 |
| B | HOH1058 |
| B | HOH1181 |
| B | HOH1253 |
| B | HOH1476 |
| B | HOH1627 |
| B | HOH1648 |
| B | HOH1694 |
| B | HOH1834 |
| B | HOH2427 |
| B | HOH2702 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MES A 902 |
| Chain | Residue |
| A | LEU121 |
| A | VAL122 |
| A | VAL123 |
| A | TRP131 |
| A | ALA133 |
| A | PHE137 |
| A | HOH2233 |
| A | HOH2491 |
| B | SER462 |
| B | ILE463 |
| B | ASP464 |
| B | LEU467 |
| D | LEU149 |
| site_id | AC5 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE FAD C 801 |
| Chain | Residue |
| C | ILE57 |
| C | ASP76 |
| C | ILE77 |
| C | THR158 |
| C | ARG159 |
| C | VAL160 |
| C | GLY163 |
| C | MET164 |
| C | HIS167 |
| C | TRP168 |
| C | THR169 |
| C | CYS170 |
| C | ALA171 |
| C | VAL281 |
| C | CYS283 |
| C | THR319 |
| C | ALA320 |
| C | HIS324 |
| C | LEU547 |
| C | ASN593 |
| C | THR595 |
| C | HOH1076 |
| C | HOH1399 |
| C | HOH1453 |
| C | HOH1493 |
| C | HOH1767 |
| C | HOH1803 |
| C | HOH2272 |
| C | HOH3215 |
| C | HOH3495 |
| C | VAL52 |
| C | GLY53 |
| C | GLY55 |
| C | PRO56 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE MES D 903 |
| Chain | Residue |
| A | LEU149 |
| C | SER462 |
| C | ILE463 |
| C | ASP464 |
| C | LEU467 |
| D | LEU121 |
| D | VAL122 |
| D | VAL123 |
| D | TRP131 |
| D | ALA133 |
| D | PHE137 |
| D | HOH1743 |
| D | HOH1874 |
| D | HOH3055 |
| site_id | AC7 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE FAD D 801 |
| Chain | Residue |
| D | GLY53 |
| D | GLY55 |
| D | PRO56 |
| D | ILE57 |
| D | ASP76 |
| D | ILE77 |
| D | THR158 |
| D | ARG159 |
| D | VAL160 |
| D | GLY163 |
| D | MET164 |
| D | HIS167 |
| D | TRP168 |
| D | THR169 |
| D | CYS170 |
| D | ALA171 |
| D | VAL281 |
| D | CYS283 |
| D | THR319 |
| D | ALA320 |
| D | HIS324 |
| D | LEU547 |
| D | ASN593 |
| D | THR595 |
| D | HOH1231 |
| D | HOH1265 |
| D | HOH1296 |
| D | HOH1529 |
| D | HOH1592 |
| D | HOH1801 |
| D | HOH1807 |
| D | HOH1963 |
| D | HOH2618 |
| D | HOH2663 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MES C 904 |
| Chain | Residue |
| C | LEU121 |
| C | VAL123 |
| C | TRP131 |
| C | ALA133 |
| C | PHE137 |
| C | HOH1853 |
| C | HOH1926 |
| D | SER462 |
| D | ILE463 |
| D | ASP464 |
| D | LEU467 |
| site_id | AC9 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE FAD E 801 |
| Chain | Residue |
| E | GLY53 |
| E | GLY55 |
| E | PRO56 |
| E | ILE57 |
| E | ASP76 |
| E | ILE77 |
| E | THR158 |
| E | ARG159 |
| E | VAL160 |
| E | GLY163 |
| E | MET164 |
| E | HIS167 |
| E | TRP168 |
| E | THR169 |
| E | CYS170 |
| E | ALA171 |
| E | VAL281 |
| E | CYS283 |
| E | THR319 |
| E | ALA320 |
| E | HIS324 |
| E | LEU547 |
| E | ASN593 |
| E | THR595 |
| E | HOH1286 |
| E | HOH1590 |
| E | HOH1595 |
| E | HOH1652 |
| E | HOH1766 |
| E | HOH2037 |
| E | HOH2097 |
| E | HOH2260 |
| E | HOH3016 |
| site_id | BC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MES E 905 |
| Chain | Residue |
| E | SER462 |
| E | ILE463 |
| E | ASP464 |
| E | LEU467 |
| E | HOH1311 |
| E | HOH2488 |
| F | LEU121 |
| F | VAL123 |
| F | TRP131 |
| F | GLN132 |
| F | ALA133 |
| F | PHE137 |
| G | LEU149 |
| site_id | BC2 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD F 801 |
| Chain | Residue |
| F | VAL52 |
| F | GLY53 |
| F | GLY55 |
| F | PRO56 |
| F | ILE57 |
| F | ASP76 |
| F | ILE77 |
| F | THR158 |
| F | ARG159 |
| F | VAL160 |
| F | GLY163 |
| F | MET164 |
| F | SER165 |
| F | HIS167 |
| F | TRP168 |
| F | THR169 |
| F | CYS170 |
| F | ALA171 |
| F | VAL281 |
| F | CYS283 |
| F | THR319 |
| F | ALA320 |
| F | HIS324 |
| F | LEU547 |
| F | ASN593 |
| F | THR595 |
| F | HOH1198 |
| F | HOH1670 |
| F | HOH1673 |
| F | HOH1700 |
| F | HOH1790 |
| F | HOH1796 |
| F | HOH1827 |
| F | HOH1828 |
| F | HOH2066 |
| F | HOH2367 |
| F | HOH3359 |
| site_id | BC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MES E 906 |
| Chain | Residue |
| E | LEU121 |
| E | VAL122 |
| E | VAL123 |
| E | TRP131 |
| E | ALA133 |
| E | PHE137 |
| E | HOH1841 |
| E | HOH2112 |
| F | SER462 |
| F | ILE463 |
| F | ASP464 |
| F | LEU467 |
| H | LEU149 |
| site_id | BC4 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD G 801 |
| Chain | Residue |
| G | VAL52 |
| G | GLY53 |
| G | GLY55 |
| G | PRO56 |
| G | ILE57 |
| G | ASP76 |
| G | ILE77 |
| G | THR158 |
| G | ARG159 |
| G | VAL160 |
| G | GLY163 |
| G | MET164 |
| G | HIS167 |
| G | TRP168 |
| G | THR169 |
| G | CYS170 |
| G | ALA171 |
| G | VAL281 |
| G | CYS283 |
| G | THR319 |
| G | ALA320 |
| G | HIS324 |
| G | LEU547 |
| G | HIS548 |
| G | ASN593 |
| G | THR595 |
| G | HOH1109 |
| G | HOH1216 |
| G | HOH1337 |
| G | HOH1370 |
| G | HOH1464 |
| G | HOH1659 |
| G | HOH1975 |
| G | HOH2665 |
| G | HOH3137 |
| G | HOH3203 |
| G | HOH3524 |
| site_id | BC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MES H 907 |
| Chain | Residue |
| E | LEU149 |
| G | SER462 |
| G | ILE463 |
| G | ASP464 |
| G | LEU467 |
| H | LEU121 |
| H | VAL123 |
| H | TRP131 |
| H | GLN132 |
| H | ALA133 |
| H | PHE137 |
| H | HOH2169 |
| H | HOH2336 |
| site_id | BC6 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE FAD H 801 |
| Chain | Residue |
| H | VAL52 |
| H | GLY53 |
| H | GLY55 |
| H | PRO56 |
| H | ILE57 |
| H | ASP76 |
| H | ILE77 |
| H | THR158 |
| H | ARG159 |
| H | VAL160 |
| H | GLY163 |
| H | MET164 |
| H | HIS167 |
| H | TRP168 |
| H | THR169 |
| H | CYS170 |
| H | ALA171 |
| H | VAL281 |
| H | CYS283 |
| H | THR319 |
| H | ALA320 |
| H | HIS324 |
| H | LEU547 |
| H | HIS548 |
| H | ASN593 |
| H | THR595 |
| H | HOH1049 |
| H | HOH1101 |
| H | HOH1132 |
| H | HOH1209 |
| H | HOH1345 |
| H | HOH1515 |
| H | HOH1719 |
| H | HOH2385 |
| H | HOH3290 |
| H | HOH3763 |
| site_id | BC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE MES G 908 |
| Chain | Residue |
| F | LEU149 |
| G | LEU121 |
| G | VAL123 |
| G | TRP131 |
| G | ALA133 |
| G | PHE137 |
| G | ARG139 |
| G | HOH1962 |
| G | HOH1977 |
| G | HOH3160 |
| H | SER462 |
| H | ILE463 |
| H | ASP464 |
| H | LEU467 |
