2HEY

Crystal structure of murine OX40L bound to human OX40

Functional Information from GO Data

Chain	GOid	namespace	contents
F	0005125	molecular_function	cytokine activity
F	0005164	molecular_function	tumor necrosis factor receptor binding
F	0006955	biological_process	immune response
F	0016020	cellular_component	membrane
G	0005125	molecular_function	cytokine activity
G	0005164	molecular_function	tumor necrosis factor receptor binding
G	0006955	biological_process	immune response
G	0016020	cellular_component	membrane
R	0005031	molecular_function	tumor necrosis factor receptor activity
R	0006954	biological_process	inflammatory response
T	0005031	molecular_function	tumor necrosis factor receptor activity
T	0006954	biological_process	inflammatory response

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 R 171

Chain	Residue
R	ARG41
R	CYS43
R	HIS44
R	ARG47
R	ASN61
R	THR62
R	HOH178

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Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	TNF_1 TNF family signature. VvIKcDGLYIIylKGsF

Chain	Residue	Details
F	VAL94-PHE110

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site_id	PS00652
Number of Residues	34
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Cvgdt..Ypsndr.....C..Che.Crpgngmvsr..Csrsq..NTVC

Chain	Residue	Details
R	CYS31-CYS64
R	CYS64-CYS107

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
R	ASN146
R	ASN160
T	ASN146
T	ASN160

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16905106

Chain	Residue	Details
F	ASN91
G	ASN91

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