2FYK
Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in complex with ADP and Biotin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004077 | molecular_function | biotin-[acetyl-CoA-carboxylase] ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016874 | molecular_function | ligase activity |
| A | 0036211 | biological_process | protein modification process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004077 | molecular_function | biotin-[acetyl-CoA-carboxylase] ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016874 | molecular_function | ligase activity |
| B | 0036211 | biological_process | protein modification process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP A 1301 |
| Chain | Residue |
| A | ARG48 |
| A | BTN1401 |
| A | HOH1439 |
| A | HOH1526 |
| A | HOH1639 |
| A | HOH1645 |
| A | HOH1653 |
| A | HOH1678 |
| A | HOH1685 |
| A | HOH1686 |
| A | ARG51 |
| A | LYS52 |
| A | TRP53 |
| A | GLU54 |
| A | ASP104 |
| A | LYS111 |
| A | ASN131 |
| A | ALA140 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP B 1302 |
| Chain | Residue |
| B | ARG48 |
| B | ARG51 |
| B | LYS52 |
| B | TRP53 |
| B | GLU54 |
| B | ASN103 |
| B | ASP104 |
| B | LYS111 |
| B | ASN131 |
| B | ALA140 |
| B | BTN1402 |
| B | HOH1464 |
| B | HOH1476 |
| B | HOH1576 |
| B | HOH1589 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE BTN A 1401 |
| Chain | Residue |
| A | SER21 |
| A | THR22 |
| A | ASN23 |
| A | GLN42 |
| A | GLY45 |
| A | HIS46 |
| A | TRP53 |
| A | LEU62 |
| A | ASN103 |
| A | ASP104 |
| A | LYS111 |
| A | GLY114 |
| A | VAL115 |
| A | ILE128 |
| A | GLY129 |
| A | ADP1301 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE BTN B 1402 |
| Chain | Residue |
| B | SER21 |
| B | THR22 |
| B | ASN23 |
| B | GLN42 |
| B | GLY45 |
| B | HIS46 |
| B | GLY47 |
| B | ARG48 |
| B | TRP53 |
| B | LEU62 |
| B | ASN103 |
| B | ASP104 |
| B | LYS111 |
| B | GLY114 |
| B | VAL115 |
| B | ILE128 |
| B | GLY129 |
| B | ADP1302 |
