2FON

X-ray crystal structure of LeACX1, an acyl-CoA oxidase from Lycopersicon esculentum (tomato)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000038	biological_process	very long-chain fatty acid metabolic process
A	0000166	molecular_function	nucleotide binding
A	0001676	biological_process	long-chain fatty acid metabolic process
A	0003997	molecular_function	acyl-CoA oxidase activity
A	0005504	molecular_function	fatty acid binding
A	0005777	cellular_component	peroxisome
A	0006631	biological_process	fatty acid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0016401	molecular_function	palmitoyl-CoA oxidase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0055088	biological_process	lipid homeostasis
A	0071949	molecular_function	FAD binding
A	1904070	biological_process	ascaroside biosynthetic process
B	0000038	biological_process	very long-chain fatty acid metabolic process
B	0000166	molecular_function	nucleotide binding
B	0001676	biological_process	long-chain fatty acid metabolic process
B	0003997	molecular_function	acyl-CoA oxidase activity
B	0005504	molecular_function	fatty acid binding
B	0005777	cellular_component	peroxisome
B	0006631	biological_process	fatty acid metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0016401	molecular_function	palmitoyl-CoA oxidase activity
B	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
B	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
B	0050660	molecular_function	flavin adenine dinucleotide binding
B	0055088	biological_process	lipid homeostasis
B	0071949	molecular_function	FAD binding
B	1904070	biological_process	ascaroside biosynthetic process
C	0000038	biological_process	very long-chain fatty acid metabolic process
C	0000166	molecular_function	nucleotide binding
C	0001676	biological_process	long-chain fatty acid metabolic process
C	0003997	molecular_function	acyl-CoA oxidase activity
C	0005504	molecular_function	fatty acid binding
C	0005777	cellular_component	peroxisome
C	0006631	biological_process	fatty acid metabolic process
C	0006635	biological_process	fatty acid beta-oxidation
C	0016401	molecular_function	palmitoyl-CoA oxidase activity
C	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
C	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
C	0050660	molecular_function	flavin adenine dinucleotide binding
C	0055088	biological_process	lipid homeostasis
C	0071949	molecular_function	FAD binding
C	1904070	biological_process	ascaroside biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	BINDING SITE FOR RESIDUE FAD A 1000

Chain	Residue
A	LEU101
A	ASN239
A	PRO419
A	THR422
A	TYR423
A	ASP426
A	VAL429
A	LEU432
B	ARG310
B	GLN312
B	PHE313
A	TYR135
B	VAL324
B	TYR327
B	THR329
B	GLN330
B	ARG333
B	LEU398
B	GLY401
A	GLN137
A	THR138
A	GLY143
A	SER144
A	TRP175
A	PRO176
A	GLY177

---

site_id	AC2
Number of Residues	25
Details	BINDING SITE FOR RESIDUE FAD B 2000

Chain	Residue
A	ARG310
A	PHE313
A	VAL324
A	TYR327
A	THR329
A	GLN330
A	ARG333
A	LEU398
A	GLY400
A	GLY401
B	LEU101
B	TYR135
B	GLN137
B	THR138
B	GLY143
B	SER144
B	TRP175
B	PRO176
B	GLY177
B	PRO419
B	THR422
B	TYR423
B	ASP426
B	VAL429
B	LEU432

---

site_id	AC3
Number of Residues	26
Details	BINDING SITE FOR RESIDUE FAD C 3000

Chain	Residue
C	LEU101
C	TYR135
C	GLN137
C	THR138
C	GLY143
C	SER144
C	TRP175
C	PRO176
C	GLY177
C	ASN239
C	ARG310
C	GLN312
C	PHE313
C	VAL324
C	TYR327
C	GLN330
C	ARG333
C	LEU398
C	GLY400
C	GLY401
C	TYR404
C	PRO419
C	THR422
C	ASP426
C	VAL428
C	VAL429

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