2EYQ

Crystal structure of Escherichia coli transcription-repair coupling factor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000716	biological_process	transcription-coupled nucleotide-excision repair, DNA damage recognition
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0004386	molecular_function	helicase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006281	biological_process	DNA repair
A	0006283	biological_process	transcription-coupled nucleotide-excision repair
A	0006294	biological_process	nucleotide-excision repair, preincision complex assembly
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006974	biological_process	DNA damage response
A	0015616	molecular_function	DNA translocase activity
A	0016787	molecular_function	hydrolase activity
A	0043175	molecular_function	RNA polymerase core enzyme binding
A	1990391	cellular_component	DNA repair complex
B	0000716	biological_process	transcription-coupled nucleotide-excision repair, DNA damage recognition
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006281	biological_process	DNA repair
B	0006283	biological_process	transcription-coupled nucleotide-excision repair
B	0006294	biological_process	nucleotide-excision repair, preincision complex assembly
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006974	biological_process	DNA damage response
B	0015616	molecular_function	DNA translocase activity
B	0016787	molecular_function	hydrolase activity
B	0043175	molecular_function	RNA polymerase core enzyme binding
B	1990391	cellular_component	DNA repair complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1149

Chain	Residue
A	THR658
A	THR659
A	LEU660
A	ARG685
B	HIS842

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 1150

Chain	Residue
A	ARG395
A	ARG411

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 1149

Chain	Residue
B	ARG395
B	ARG411

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE B 1150

Chain	Residue
A	HIS842
B	THR658
B	THR659
B	LEU660
B	ARG685
B	THR710
B	HIS711
B	LYS712

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE EPE A 1151

Chain	Residue
A	HIS897
A	ARG900
A	LEU936
A	GLU937
A	ASP938
A	LEU939
A	GLY940
A	ALA941
A	GLY942
A	PHE943
A	HOH1166

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE B 1151

Chain	Residue
B	HIS897
B	ARG900
B	LEU936
B	GLU937
B	ASP938
B	LEU939
B	GLY940
B	ALA941
B	GLY942
B	PHE943

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EPE A 1152

Chain	Residue
A	GLN459
A	ARG462
A	ARG782
A	ARG905
A	SER906
A	HIS907

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EPE B 1152

Chain	Residue
B	SER461
B	ARG782
B	ARG905
B	SER906
B	HIS907

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00969

Chain	Residue	Details
A	GLY628
B	GLY628

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