2EGG
Crystal Structure of Shikimate 5-Dehydrogenase (AroE) from Geobacillus kaustophilus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019632 | biological_process | shikimate metabolic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019632 | biological_process | shikimate metabolic process |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1001 |
| Chain | Residue |
| A | MET265 |
| A | GLN269 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1002 |
| Chain | Residue |
| A | ASN113 |
| A | ARG116 |
| A | ARG180 |
| A | HOH1075 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00222 |
| Chain | Residue | Details |
| A | LYS87 | |
| B | LYS87 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00222 |
| Chain | Residue | Details |
| A | GLU99 | |
| A | ASN108 | |
| A | ASP123 | |
| A | ASN172 | |
| A | ILE239 | |
| A | TYR241 | |
| A | GLY262 | |
| B | SER36 | |
| B | THR83 | |
| B | GLU99 | |
| B | ASN108 | |
| B | ASP123 | |
| B | ASN172 | |
| B | ILE239 | |
| B | TYR241 | |
| B | GLY262 | |
| A | SER36 | |
| A | THR83 |
