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2DEK

Crystal structure of project ID PH0725 from Pyrococcus horikoshii OT3 at 1.65 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0004164molecular_functiondiphthine synthase activity
A0008168molecular_functionmethyltransferase activity
A0017183biological_processprotein histidyl modification to diphthamide
A0032259biological_processmethylation
B0004164molecular_functiondiphthine synthase activity
B0008168molecular_functionmethyltransferase activity
B0017183biological_processprotein histidyl modification to diphthamide
B0032259biological_processmethylation
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA A 1500
ChainResidue
ATYR117
AHOH1502
AHOH1509
BHOH266
BHOH268

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE SAH A 1300
ChainResidue
AASP87
AVAL90
ASER115
AILE116
APHE165
ALEU166
ALEU206
AARG208
AALA209
APRO233
AHIS234
AHOH1527
AHOH1535
AHOH1552
ALEU10
ATHR36
ASER37
AGLY86

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01084, ECO:0000305|PubMed:18391406, ECO:0000305|Ref.4
ChainResidueDetails
ALEU10
BVAL90
BSER115
BLEU166
BALA209
BHIS234
AASP87
AVAL90
ASER115
ALEU166
AALA209
AHIS234
BLEU10
BASP87

220113

PDB entries from 2024-05-22

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