2AEP

An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004308	molecular_function	exo-alpha-sialidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0016020	cellular_component	membrane
A	0033644	cellular_component	host cell membrane
A	0046761	biological_process	viral budding from plasma membrane
A	0055036	cellular_component	virion membrane
H	0002250	biological_process	adaptive immune response
H	0003823	molecular_function	antigen binding
H	0005576	cellular_component	extracellular region
H	0016064	biological_process	immunoglobulin mediated immune response
H	0019814	cellular_component	immunoglobulin complex
L	0002250	biological_process	adaptive immune response
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0006955	biological_process	immune response
L	0019814	cellular_component	immunoglobulin complex

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CsCypRypGVrC

Chain	Residue	Details
A	CYS278-CYS289

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1a4g

Chain	Residue	Details
A	ASP151
A	GLU277

---