2AB2
Mineralocorticoid Receptor Double Mutant with Bound Spironolactone
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| A | HOH102 |
| A | PRO759 |
| A | ASP760 |
| B | SER756 |
| B | SER757 |
| B | LYS953 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SNL A 502 |
| Chain | Residue |
| A | ALA773 |
| A | GLN776 |
| A | MET807 |
| A | LEU810 |
| A | ARG817 |
| A | PHE829 |
| A | MET845 |
| A | MET852 |
| A | PHE941 |
| A | CYS942 |
| A | THR945 |
| A | PHE956 |
| A | LEU766 |
| A | LEU769 |
| A | ASN770 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SNL B 503 |
| Chain | Residue |
| B | LEU766 |
| B | LEU769 |
| B | ASN770 |
| B | ALA773 |
| B | GLN776 |
| B | MET807 |
| B | LEU810 |
| B | ARG817 |
| B | PHE829 |
| B | MET845 |
| B | MET852 |
| B | PHE941 |
| B | CYS942 |
| B | THR945 |
| B | PHE956 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15908963, ECO:0000269|PubMed:15967794, ECO:0007744|PDB:1YA3, ECO:0007744|PDB:2AA5, ECO:0007744|PDB:2AA6 |
| Chain | Residue | Details |
| A | ASN770 | |
| A | GLN776 | |
| A | ARG817 | |
| B | ASN770 | |
| B | GLN776 | |
| B | ARG817 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15967794, ECO:0007744|PDB:2AA5, ECO:0007744|PDB:2AA6 |
| Chain | Residue | Details |
| A | THR945 | |
| B | THR945 |
