Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003920 | molecular_function | GMP reductase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006163 | biological_process | purine nucleotide metabolic process |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 1902560 | cellular_component | GMP reductase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE 5GP A 1344 |
| Chain | Residue |
| A | ALA43 |
| A | ARG211 |
| A | MET228 |
| A | GLY230 |
| A | SER231 |
| A | TYR254 |
| A | GLY256 |
| A | SER257 |
| A | HOH1345 |
| A | HOH1366 |
| A | HOH1444 |
| A | MET45 |
| A | HOH1447 |
| A | HOH1473 |
| A | HOH1480 |
| A | GLY172 |
| A | LYS173 |
| A | CYS175 |
| A | THR177 |
| A | ASP207 |
| A | GLY208 |
| A | GLY209 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. TKVGIGpGKVCiT |
| Chain | Residue | Details |
| A | THR165-THR177 | |
| site_id | PS00912 |
| Number of Residues | 21 |
| Details | DHODEHASE_2 Dihydroorotate dehydrogenase signature 2. IIAdGGIrTngdVakSIrFGA |
| Chain | Residue | Details |
| A | ILE204-ALA224 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS175 | |
| Chain | Residue | Details |
| A | ILE204 | |
