1YIR
Crystal Structure of a Nicotinate Phosphoribosyltransferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0009435 | biological_process | NAD biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| A | 0034355 | biological_process | NAD salvage |
| B | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0009435 | biological_process | NAD biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| B | 0034355 | biological_process | NAD salvage |
| C | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0009435 | biological_process | NAD biosynthetic process |
| C | 0016874 | molecular_function | ligase activity |
| C | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| C | 0034355 | biological_process | NAD salvage |
| D | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0009435 | biological_process | NAD biosynthetic process |
| D | 0016874 | molecular_function | ligase activity |
| D | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| D | 0034355 | biological_process | NAD salvage |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2000 |
| Chain | Residue |
| A | ARG11 |
| A | ASN15 |
| A | HIS211 |
| A | HOH2104 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| A | HOH2145 |
| A | TYR22 |
| A | ARG181 |
| A | ALA225 |
| A | HIS226 |
| A | ARG287 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2002 |
| Chain | Residue |
| A | GLY321 |
| A | GLY345 |
| A | THR346 |
| A | HOH2041 |
| A | HOH2142 |
| A | HOH2144 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 3000 |
| Chain | Residue |
| B | ARG11 |
| B | ASN15 |
| B | HOH3162 |
| B | HOH3196 |
| B | HOH3197 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 3001 |
| Chain | Residue |
| B | TYR22 |
| B | ALA225 |
| B | HIS226 |
| B | LEU262 |
| B | ARG287 |
| B | HOH3107 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 3002 |
| Chain | Residue |
| B | ARG182 |
| B | GLY321 |
| B | GLY345 |
| B | THR346 |
| B | HOH3019 |
| B | HOH3114 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 4001 |
| Chain | Residue |
| C | ARG11 |
| C | ASN15 |
| C | HIS211 |
| C | HOH4074 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 4002 |
| Chain | Residue |
| C | ARG182 |
| C | GLY321 |
| C | GLY345 |
| C | THR346 |
| C | HOH4066 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 4003 |
| Chain | Residue |
| C | TYR22 |
| C | ALA225 |
| C | HIS226 |
| C | LEU262 |
| C | ARG287 |
| C | HOH4045 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 5000 |
| Chain | Residue |
| D | ARG11 |
| D | ASN15 |
| D | HIS211 |
| D | HOH5022 |
| D | HOH5055 |
| D | HOH5057 |
| D | HOH5129 |
| D | HOH5168 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 5001 |
| Chain | Residue |
| D | TYR22 |
| D | ALA225 |
| D | HIS226 |
| D | LEU262 |
| D | ARG287 |
| D | HOH5162 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 5002 |
| Chain | Residue |
| D | ARG182 |
| D | GLY321 |
| D | GLY345 |
| D | THR346 |
| D | HOH5016 |
| D | HOH5217 |
| D | HOH5218 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphohistidine; by autocatalysis => ECO:0000255|HAMAP-Rule:MF_00570 |
| Chain | Residue | Details |
| A | HIS226 | |
| B | HIS226 | |
| C | HIS226 | |
| D | HIS226 |
