1XWV
Structure of the house dust mite allergen Der f 2: Implications for function and molecular basis of IgE cross-reactivity
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0015485 | molecular_function | cholesterol binding |
| A | 0015918 | biological_process | sterol transport |
| A | 0032367 | biological_process | intracellular cholesterol transport |
| A | 0032934 | molecular_function | sterol binding |
| A | 0033344 | biological_process | cholesterol efflux |
| B | 0005576 | cellular_component | extracellular region |
| B | 0015485 | molecular_function | cholesterol binding |
| B | 0015918 | biological_process | sterol transport |
| B | 0032367 | biological_process | intracellular cholesterol transport |
| B | 0032934 | molecular_function | sterol binding |
| B | 0033344 | biological_process | cholesterol efflux |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PE3 A 1001 |
| Chain | Residue |
| A | ASP4 |
| A | TYR90 |
| A | TRP92 |
| A | PRO95 |
| A | ILE97 |
| A | VAL108 |
| A | ALA122 |
| A | HIS124 |
| A | ALA125 |
| B | ILE97 |
| B | PRO99 |
| A | VAL18 |
| A | CYS27 |
| A | PHE35 |
| A | LEU37 |
| A | ILE54 |
| A | ASP64 |
| A | PRO66 |
| A | ALA88 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE XPE B 1002 |
| Chain | Residue |
| B | ASP4 |
| B | CYS27 |
| B | ILE29 |
| B | PHE35 |
| B | LEU37 |
| B | ALA39 |
| B | ILE52 |
| B | TYR90 |
| B | TRP92 |
| B | ALA122 |
| B | THR123 |
| B | HIS124 |
