Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008675 | molecular_function | 2-dehydro-3-deoxy-phosphogluconate aldolase activity |
| A | 0008700 | molecular_function | 4-hydroxy-2-oxoglutarate aldolase activity |
| A | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016833 | molecular_function | oxo-acid-lyase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0106009 | molecular_function | (4S)-4-hydroxy-2-oxoglutarate aldolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A1214 |
| Chain | Residue |
| A | GLY162 |
| A | GLY163 |
| A | ILE164 |
| A | SER184 |
| A | HOH2098 |
| A | HOH2100 |
| A | HOH2101 |
| A | HOH2102 |
Functional Information from PROSITE/UniProt
| site_id | PS00160 |
| Number of Residues | 14 |
| Details | ALDOLASE_KDPG_KHG_2 KDPG and KHG aldolases Schiff-base forming residue. GlkeFKFFPAeanG |
| Chain | Residue | Details |
| A | GLY128-GLY141 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | ASN45 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ARG49 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: Schiff-base intermediate with substrate |
| Chain | Residue | Details |
| A | LYS133 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | THR73 | |
| A | THR161 | |
| A | GLY163 | |
| A | SER184 | |
| A | ARG49 | |
| Chain | Residue | Details |
| A | LYS133 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | SITE: Plays a major role in determining the stereoselectivity |
| Chain | Residue | Details |
| A | THR161 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 550 |
| Chain | Residue | Details |
| A | ASN45 | proton acceptor, proton donor |
| A | ARG49 | electrostatic stabiliser, modifies pKa |
| A | LYS133 | electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor |
