1VP2

CRYSTAL STRUCTURE OF A PUTATIVE XANTHOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN HOMOLOG (TM0159) FROM THERMOTOGA MARITIMA AT 1.78 A RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009117	biological_process	nucleotide metabolic process
A	0009143	biological_process	nucleoside triphosphate catabolic process
A	0009146	biological_process	purine nucleoside triphosphate catabolic process
A	0016787	molecular_function	hydrolase activity
A	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
A	0035870	molecular_function	dITP diphosphatase activity
A	0036220	molecular_function	ITP diphosphatase activity
A	0036222	molecular_function	XTP diphosphatase activity
A	0046872	molecular_function	metal ion binding
A	0047429	molecular_function	nucleoside triphosphate diphosphatase activity
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009117	biological_process	nucleotide metabolic process
B	0009143	biological_process	nucleoside triphosphate catabolic process
B	0009146	biological_process	purine nucleoside triphosphate catabolic process
B	0016787	molecular_function	hydrolase activity
B	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
B	0035870	molecular_function	dITP diphosphatase activity
B	0036220	molecular_function	ITP diphosphatase activity
B	0036222	molecular_function	XTP diphosphatase activity
B	0046872	molecular_function	metal ion binding
B	0047429	molecular_function	nucleoside triphosphate diphosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 197

Chain	Residue
A	THR10
A	ASN12
A	LYS15
A	LYS52
A	ASP67
A	HOH214
A	HOH264

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 197

Chain	Residue
B	LYS52
B	ASP67
B	HOH203
B	HOH237
B	HOH257
B	THR10
B	LYS15

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site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 198

Chain	Residue
A	ALA139
A	ASN140
A	ARG143
A	ILE155
A	HOH218
A	HOH268
A	HOH289
A	HOH314
B	HOH311

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site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 198

Chain	Residue
A	HOH241
B	ARG137
B	ASN140
B	ARG143
B	ILE155
B	HOH239
B	HOH264
B	HOH310

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01405

Chain	Residue	Details
A	ASP68
B	ASP68

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site_id	SWS_FT_FI2
Number of Residues	10
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01405

Chain	Residue	Details
A	THR10
B	HIS175
A	ASP68
A	SER69
A	PHE148
A	HIS175
B	THR10
B	ASP68
B	SER69
B	PHE148

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