1VC4
Crystal Structure of Indole-3-Glycerol Phosphate Synthase (TrpC) from Thermus Thermophilus At 1.8 A Resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | tryptophan biosynthetic process |
| A | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| A | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0043436 | biological_process | oxoacid metabolic process |
| B | 0000162 | biological_process | tryptophan biosynthetic process |
| B | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| B | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0043436 | biological_process | oxoacid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| A | LYS53 |
| A | SER215 |
| A | GLY216 |
| A | ILE235 |
| A | GLY236 |
| A | THR237 |
| A | HOH3007 |
| A | HOH3064 |
| A | HOH3149 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2002 |
| Chain | Residue |
| A | ARG43 |
| A | ARG80 |
| A | HOH3031 |
| A | HOH3181 |
| B | ARG43 |
| B | ARG80 |
| B | HOH3012 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2003 |
| Chain | Residue |
| B | LYS53 |
| B | SER215 |
| B | GLY216 |
| B | ILE235 |
| B | GLY236 |
| B | THR237 |
| B | HOH3006 |
| B | HOH3039 |
| B | HOH3048 |
| B | HOH3245 |
| B | HOH3346 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2004 |
| Chain | Residue |
| A | LYS53 |
| A | SER56 |
| A | PRO57 |
| A | SER58 |
| A | PHE91 |
| A | THR237 |
| A | HOH3050 |
| A | HOH3126 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2005 |
| Chain | Residue |
| B | THR163 |
| B | GLU164 |
| B | ARG197 |
| B | HOH3071 |
| B | HOH3192 |
| B | HOH3230 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2006 |
| Chain | Residue |
| B | MET1 |
| B | ARG2 |
| B | ARG76 |
| B | HOH3047 |
| B | HOH3198 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2007 |
| Chain | Residue |
| A | THR163 |
| A | ARG165 |
| A | HOH3302 |
| B | HOH3337 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2008 |
| Chain | Residue |
| A | THR163 |
| A | GLU164 |
| A | ARG197 |
| A | HOH3212 |
| A | HOH3302 |
| B | LYS220 |
| B | GLU251 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2009 |
| Chain | Residue |
| A | PRO44 |
| A | GLY45 |
| A | HOH3326 |
| B | ARG250 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2010 |
| Chain | Residue |
| A | ARG250 |
| B | PRO44 |
| B | GLY45 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 3001 |
| Chain | Residue |
| A | MET1 |
| A | ARG2 |
| A | HOH3114 |
| A | HOH3275 |
| A | HOH3292 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACY B 3002 |
| Chain | Residue |
| B | LYS53 |
| B | SER58 |
| B | ARG183 |
| B | HOH3049 |
| B | HOH3051 |
| B | HOH3058 |
| B | HOH3346 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY B 3003 |
| Chain | Residue |
| B | ARG63 |
| B | PRO243 |
| B | ASP244 |
| B | LEU245 |
| B | HOH3024 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 3004 |
| Chain | Residue |
| A | SER33 |
| A | VAL34 |
| A | ARG125 |
| A | HOH3063 |
| A | HOH3077 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY B 3005 |
| Chain | Residue |
| B | ARG19 |
| B | ARG111 |
| B | MET120 |
| B | GLU123 |
| B | HOH3138 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1001 |
| Chain | Residue |
| B | LEU201 |
| B | ARG205 |
| B | HOH3325 |
