1VA0
Crystal Structure of the Native Form of Uroporphyrin III C-methyl transferase from Thermus thermophilus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004851 | molecular_function | uroporphyrin-III C-methyltransferase activity |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0019354 | biological_process | siroheme biosynthetic process |
| A | 0032259 | biological_process | methylation |
| B | 0004851 | molecular_function | uroporphyrin-III C-methyltransferase activity |
| B | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0019354 | biological_process | siroheme biosynthetic process |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 501 |
| Chain | Residue |
| A | ASP86 |
| A | THR114 |
| A | SER115 |
| A | HOH608 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| B | GLY85 |
| B | ASP86 |
| B | THR114 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 503 |
| Chain | Residue |
| B | GLY207 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 601 |
| Chain | Residue |
| A | ARG177 |
| A | ASP178 |
| A | HOH648 |
| A | ARG152 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 602 |
| Chain | Residue |
| B | ARG152 |
| B | ARG177 |
| B | HOH643 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 603 |
| Chain | Residue |
| A | PRO77 |
| B | ARG195 |
| B | VAL209 |
| B | GLU210 |
| B | HOH719 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 604 |
| Chain | Residue |
| A | ARG102 |
| B | LYS26 |
| B | GLU228 |
| B | HOH658 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 605 |
| Chain | Residue |
| A | TYR5 |
| A | ARG23 |
| A | GLU27 |
| A | PHE78 |
Functional Information from PROSITE/UniProt
| site_id | PS00839 |
| Number of Residues | 15 |
| Details | SUMT_1 Uroporphyrin-III C-methyltransferase signature 1. VGAGPGdpeLLTLKA |
| Chain | Residue | Details |
| A | VAL7-ALA21 |
| site_id | PS00840 |
| Number of Residues | 34 |
| Details | SUMT_2 Uroporphyrin-III C-methyltransferase signature 2. VvrLkgGDpmvFGrggeevlfLlrhgvpVeVvPG |
| Chain | Residue | Details |
| A | VAL79-GLY112 |
