1V7C
Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
Replaces: 1UIQFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004795 | molecular_function | threonine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0009088 | biological_process | threonine biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 1901605 | biological_process | alpha-amino acid metabolic process |
| B | 0004795 | molecular_function | threonine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0009088 | biological_process | threonine biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 1901605 | biological_process | alpha-amino acid metabolic process |
| C | 0004795 | molecular_function | threonine synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0009088 | biological_process | threonine biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019344 | biological_process | cysteine biosynthetic process |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 1901605 | biological_process | alpha-amino acid metabolic process |
| D | 0004795 | molecular_function | threonine synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0009088 | biological_process | threonine biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019344 | biological_process | cysteine biosynthetic process |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 1901605 | biological_process | alpha-amino acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEY A 1400 |
| Chain | Residue |
| A | PHE60 |
| A | ARG160 |
| A | VAL186 |
| A | GLY187 |
| A | ASN188 |
| A | ALA189 |
| A | GLY190 |
| A | ASN191 |
| A | ALA240 |
| A | ILE241 |
| A | GLU287 |
| A | LYS61 |
| A | THR317 |
| A | HOH1402 |
| A | HOH1406 |
| A | HOH1427 |
| A | HOH1441 |
| A | HOH1465 |
| A | SER84 |
| A | THR85 |
| A | ASN87 |
| A | THR88 |
| A | PHE134 |
| A | ASN154 |
| A | SER155 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEY B 2400 |
| Chain | Residue |
| B | PHE60 |
| B | LYS61 |
| B | SER84 |
| B | THR85 |
| B | ASN87 |
| B | THR88 |
| B | PHE134 |
| B | ASN154 |
| B | SER155 |
| B | ARG160 |
| B | VAL186 |
| B | GLY187 |
| B | ASN188 |
| B | ALA189 |
| B | GLY190 |
| B | ASN191 |
| B | ALA240 |
| B | ILE241 |
| B | GLU287 |
| B | THR317 |
| B | HOH2402 |
| B | HOH2403 |
| B | HOH2413 |
| B | HOH2422 |
| B | HOH2514 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEY C 3400 |
| Chain | Residue |
| C | PHE60 |
| C | LYS61 |
| C | SER84 |
| C | THR85 |
| C | ASN87 |
| C | THR88 |
| C | PHE134 |
| C | ASN154 |
| C | SER155 |
| C | ARG160 |
| C | PRO185 |
| C | VAL186 |
| C | GLY187 |
| C | ASN188 |
| C | ALA189 |
| C | GLY190 |
| C | ASN191 |
| C | ALA240 |
| C | ILE241 |
| C | GLU287 |
| C | THR317 |
| C | HOH3408 |
| C | HOH3416 |
| C | HOH3449 |
| C | HOH3462 |
| C | HOH3512 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEY D 4400 |
| Chain | Residue |
| D | HOH4448 |
| D | HOH4581 |
| D | PHE60 |
| D | LYS61 |
| D | SER84 |
| D | THR85 |
| D | ASN87 |
| D | THR88 |
| D | PHE134 |
| D | ASN154 |
| D | SER155 |
| D | ARG160 |
| D | VAL186 |
| D | GLY187 |
| D | ASN188 |
| D | ALA189 |
| D | GLY190 |
| D | ASN191 |
| D | ALA240 |
| D | ILE241 |
| D | GLU287 |
| D | THR317 |
| D | HOH4401 |
| D | HOH4414 |
| D | HOH4442 |
Functional Information from PROSITE/UniProt
| site_id | PS00165 |
| Number of Residues | 14 |
| Details | DEHYDRATASE_SER_THR Serine/threonine dehydratases pyridoxal-phosphate attachment site. Eglnp.TGSFKDRGM |
| Chain | Residue | Details |
| A | GLU52-MET65 |
