1UKV
Structure of RabGDP-dissociation inhibitor in complex with prenylated YPT1 GTPase
Functional Information from GO Data
Chain | GOid | namespace | contents |
G | 0005092 | molecular_function | GDP-dissociation inhibitor activity |
G | 0005093 | molecular_function | Rab GDP-dissociation inhibitor activity |
G | 0005096 | molecular_function | GTPase activator activity |
G | 0005515 | molecular_function | protein binding |
G | 0005575 | cellular_component | cellular_component |
G | 0005737 | cellular_component | cytoplasm |
G | 0007264 | biological_process | small GTPase-mediated signal transduction |
G | 0015031 | biological_process | protein transport |
G | 0016192 | biological_process | vesicle-mediated transport |
Y | 0000045 | biological_process | autophagosome assembly |
Y | 0000139 | cellular_component | Golgi membrane |
Y | 0000149 | molecular_function | SNARE binding |
Y | 0000166 | molecular_function | nucleotide binding |
Y | 0000407 | cellular_component | phagophore assembly site |
Y | 0003924 | molecular_function | GTPase activity |
Y | 0005515 | molecular_function | protein binding |
Y | 0005525 | molecular_function | GTP binding |
Y | 0005737 | cellular_component | cytoplasm |
Y | 0005739 | cellular_component | mitochondrion |
Y | 0005783 | cellular_component | endoplasmic reticulum |
Y | 0005789 | cellular_component | endoplasmic reticulum membrane |
Y | 0005794 | cellular_component | Golgi apparatus |
Y | 0005795 | cellular_component | Golgi stack |
Y | 0005801 | cellular_component | cis-Golgi network |
Y | 0005829 | cellular_component | cytosol |
Y | 0005886 | cellular_component | plasma membrane |
Y | 0006886 | biological_process | intracellular protein transport |
Y | 0006888 | biological_process | endoplasmic reticulum to Golgi vesicle-mediated transport |
Y | 0006890 | biological_process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
Y | 0006914 | biological_process | autophagy |
Y | 0010008 | cellular_component | endosome membrane |
Y | 0012505 | cellular_component | endomembrane system |
Y | 0015031 | biological_process | protein transport |
Y | 0016020 | cellular_component | membrane |
Y | 0016192 | biological_process | vesicle-mediated transport |
Y | 0016236 | biological_process | macroautophagy |
Y | 0031410 | cellular_component | cytoplasmic vesicle |
Y | 0032258 | biological_process | cytoplasm to vacuole targeting by the Cvt pathway |
Y | 0032456 | biological_process | endocytic recycling |
Y | 0034045 | cellular_component | phagophore assembly site membrane |
Y | 0034497 | biological_process | protein localization to phagophore assembly site |
Y | 0034498 | biological_process | early endosome to Golgi transport |
Y | 0035493 | biological_process | SNARE complex assembly |
Y | 0035494 | biological_process | SNARE complex disassembly |
Y | 0048194 | biological_process | Golgi vesicle budding |
Y | 0048211 | biological_process | Golgi vesicle docking |
Y | 0061709 | biological_process | reticulophagy |
Y | 0090114 | biological_process | COPII-coated vesicle budding |
Y | 1900101 | biological_process | regulation of endoplasmic reticulum unfolded protein response |
Y | 1990261 | biological_process | pre-mRNA catabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG Y 1208 |
Chain | Residue |
Y | SER22 |
Y | GDP1207 |
Y | HOH1363 |
Y | HOH1364 |
Y | HOH1365 |
Y | HOH1366 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GER Y 1206 |
Chain | Residue |
G | LYS149 |
G | TYR220 |
G | CYS221 |
Y | CYS206 |
G | PRO128 |
G | LYS145 |
G | MET148 |
site_id | AC3 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE GDP Y 1207 |
Chain | Residue |
Y | GLY18 |
Y | VAL19 |
Y | GLY20 |
Y | LYS21 |
Y | SER22 |
Y | CYS23 |
Y | TYR33 |
Y | THR34 |
Y | ASP36 |
Y | TYR37 |
Y | ASN121 |
Y | LYS122 |
Y | ASP124 |
Y | LEU125 |
Y | SER151 |
Y | ALA152 |
Y | LEU153 |
Y | MG1208 |
Y | HOH1215 |
Y | HOH1221 |
Y | HOH1225 |
Y | HOH1230 |
Y | HOH1246 |
Y | HOH1283 |
Y | HOH1363 |
Y | HOH1364 |
Y | HOH1366 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14576435, ECO:0000269|PubMed:16034420, ECO:0000269|PubMed:16395334, ECO:0007744|PDB:1UKV, ECO:0007744|PDB:1YZN, ECO:0007744|PDB:2BCG |
Chain | Residue | Details |
Y | SER17 | |
Y | TYR33 | |
Y | ASN121 | |
Y | ALA152 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16034420, ECO:0007744|PDB:1YZN |
Chain | Residue | Details |
Y | GLY66 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: N-acetylmethionine => ECO:0000269|Ref.5 |
Chain | Residue | Details |
Y | MET1 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198 |
Chain | Residue | Details |
Y | SER172 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956 |
Chain | Residue | Details |
Y | SER174 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | LIPID: S-palmitoyl cysteine => ECO:0000255 |
Chain | Residue | Details |
Y | CYS23 | |
Y | CYS123 |
site_id | SWS_FT_FI7 |
Number of Residues | 1 |
Details | LIPID: S-geranylgeranyl cysteine => ECO:0000269|PubMed:10071213, ECO:0000269|PubMed:16395334 |
Chain | Residue | Details |
Y | CYS205 |
site_id | SWS_FT_FI8 |
Number of Residues | 1 |
Details | LIPID: S-geranylgeranyl cysteine => ECO:0000269|PubMed:10071213, ECO:0000269|PubMed:14576435, ECO:0000269|PubMed:16395334, ECO:0007744|PDB:1UKV |
Chain | Residue | Details |
Y | CYS206 |
site_id | SWS_FT_FI9 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
Chain | Residue | Details |
Y | LYS144 |