Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007584 | biological_process | response to nutrient |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030574 | biological_process | collagen catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0007584 | biological_process | response to nutrient |
| B | 0007586 | biological_process | digestion |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030574 | biological_process | collagen catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 247 |
| Chain | Residue |
| A | GLU77 |
| A | GLU80 |
| A | HOH271 |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 247 |
| Chain | Residue |
| B | GLU70 |
| B | ASN72 |
| B | VAL75 |
| B | GLU77 |
| B | GLU80 |
| B | HOH272 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BEN A 246 |
| Chain | Residue |
| A | ASP189 |
| A | SER190 |
| A | GLN192 |
| A | SER195 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | GLY226 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BEN B 246 |
| Chain | Residue |
| B | ASP189 |
| B | SER190 |
| B | GLN192 |
| B | SER195 |
| B | VAL213 |
| B | GLY216 |
| B | GLY219 |
| B | CYS220 |
| B | GLY226 |
| site_id | CTA |
| Number of Residues | 3 |
| Details | CATALYTIC SITE IN CHAIN A |
| Chain | Residue |
| A | HIS57 |
| A | ASN102 |
| A | SER195 |
| site_id | CTB |
| Number of Residues | 3 |
| Details | CATALYTIC SITE IN CHAIN B |
| Chain | Residue |
| B | HIS57 |
| B | ASN102 |
| B | SER195 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASN102 | |
| A | SER195 | |
| B | HIS57 | |
| B | ASN102 | |
| B | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| B | GLU70 | |
| B | ASN72 | |
| B | VAL75 | |
| B | GLU80 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Required for specificity => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP189 | |
| B | ASP189 | |
