1T9H

The crystal structure of YloQ, a circularly permuted GTPase.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0016787	molecular_function	hydrolase activity
A	0019843	molecular_function	rRNA binding
A	0042254	biological_process	ribosome biogenesis
A	0042274	biological_process	ribosomal small subunit biogenesis
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE IUM A 401

Chain	Residue
A	HIS-2
A	HOH479
A	HIS-4
A	HIS-3
A	HIS-1
A	ASN54
A	IUM407
A	ACT417
A	HOH424
A	HOH436

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE IUM A 402

Chain	Residue
A	HIS-4
A	GLU105
A	PRO111
A	PRO243
A	ARG246
A	IUM408
A	ACT416
A	HOH419
A	HOH420
A	HOH465

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE IUM A 403

Chain	Residue
A	ARG246
A	IUM404
A	IUM406
A	IUM408
A	ACT416
A	ACT418
A	HOH419
A	HOH422
A	HOH440
A	HOH463

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE IUM A 404

Chain	Residue
A	ARG30
A	GLU57
A	IUM403
A	ACT418
A	HOH422
A	HOH425
A	HOH458

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IUM A 405

Chain	Residue
A	GLU53
A	LYS56
A	GLU57
A	TYR59
A	HOH425

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE IUM A 406

Chain	Residue
A	HIS-1
A	GLU53
A	LYS56
A	IUM403
A	IUM408
A	ACT417
A	HOH422
A	HOH425
A	HOH440
A	HOH458
A	HOH587

---

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE IUM A 407

Chain	Residue
A	ARG-6
A	HIS-5
A	HIS-4
A	HIS-3
A	ASN54
A	ASP108
A	IUM401
A	HOH436
A	HOH451
A	HOH453
A	HOH607

---

site_id	AC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE IUM A 408

Chain	Residue
A	HIS-4
A	HIS-1
A	ARG246
A	IUM402
A	IUM403
A	IUM406
A	ACT417
A	HOH419
A	HOH420
A	HOH424
A	HOH440
A	HOH465

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 411

Chain	Residue
A	CYS252
A	CYS257
A	HIS259
A	CYS265

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 412

Chain	Residue
A	ASP143
A	TYR145
A	HOH549

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA A 413

Chain	Residue
A	HIS-1
A	GLU247

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 414

Chain	Residue
A	GLU210
A	HOH658
A	HOH663

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 415

Chain	Residue
A	GLU286
A	HOH521
A	HOH595

---

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT A 416

Chain	Residue
A	GLU105
A	GLY141
A	TYR142
A	PRO243
A	IUM402
A	IUM403
A	ACT418
A	HOH419

---

site_id	BC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ACT A 417

Chain	Residue
A	HIS-2
A	GLU53
A	ASN54
A	IUM401
A	IUM406
A	IUM408
A	HOH424
A	HOH440
A	HOH587

---

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A 418

Chain	Residue
A	PHE13
A	GLU57
A	GLY141
A	IUM403
A	IUM404
A	ACT416
A	HOH422

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01820

Chain	Residue	Details
A	THR116
A	GLY171

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01820, ECO:0000269|PubMed:15223319

Chain	Residue	Details
A	CYS252
A	CYS257
A	CYS265
A	HIS259

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:22544754

Chain	Residue	Details
A	THR166

---