Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CPW A 381 |
| Chain | Residue |
| A | TYR58 |
| A | LEU189 |
| A | GLU190 |
| A | MET193 |
| A | TYR217 |
| A | HOH410 |
| A | PRO86 |
| A | LEU87 |
| A | THR88 |
| A | ARG93 |
| A | LEU135 |
| A | GLY138 |
| A | SER139 |
| A | THR140 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CPW B 382 |
| Chain | Residue |
| B | TYR58 |
| B | PRO86 |
| B | LEU87 |
| B | THR88 |
| B | ARG93 |
| B | LEU135 |
| B | GLY138 |
| B | SER139 |
| B | THR140 |
| B | LEU189 |
| B | GLU190 |
| B | TYR217 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | TRANSMEM: Helical |
| Chain | Residue | Details |
| A | ASP204-GLY224 | |
| B | ALA131-VAL151 | |
| B | ASP204-GLY224 | |
| A | ALA131-VAL151 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 62 |
| Details | TOPO_DOM: Cytoplasmic |
| Chain | Residue | Details |
| B | PHE152-VAL178 | |
| B | GLU198-CYS203 | |
| A | PHE152-VAL178 | |
| A | GLU198-CYS203 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | INTRAMEM: Helical; Pore-forming |
| Chain | Residue | Details |
| B | ARG179-ASN194 | |
| A | ARG179-ASN194 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | INTRAMEM: |
| Chain | Residue | Details |
| B | GLU195-ILE197 | |
| A | GLU195-ILE197 | |
| Chain | Residue | Details |
| A | TYR58 | |
| B | TYR58 | |
| B | ARG93 | |
| A | ARG93 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | PRO86 | |
| A | PRO86 | |
| Chain | Residue | Details |
| B | THR88 | |
| A | THR88 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG61 | |
| B | ARG61 | |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | GLN241 | |
| B | GLN241 | |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE197 | |
| B | ILE197 | |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN0 | |
| B | ASN0 | |
