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1SND

STAPHYLOCOCCAL NUCLEASE DIMER CONTAINING A DELETION OF RESIDUES 114-119 COMPLEXED WITH CALCIUM CHLORIDE AND THE COMPETITIVE INHIBITOR DEOXYTHYMIDINE-3',5'-DIPHOSPHATE

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0004518molecular_functionnuclease activity
B0003676molecular_functionnucleic acid binding
B0004518molecular_functionnuclease activity
Functional Information from PROSITE/UniProt
site_idPS01123
Number of Residues25
DetailsTNASE_1 Thermonuclease family signature 1. DGDTVkLmykgqpmtf.RLllVDtPE
ChainResidueDetails
AASP19-GLU43

site_idPS01284
Number of Residues11
DetailsTNASE_2 Thermonuclease family signature 2. DKYGRgLAyIY
ChainResidueDetails
AASP83-TYR93

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:288045
ChainResidueDetails
AARG35
AGLU43
AARG87
BARG35
BGLU43
BARG87

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING:
ChainResidueDetails
AASP21
AASP40
ATHR41
BASP21
BASP40
BTHR41

Catalytic Information from CSA
site_idMCSA1
Number of Residues6
DetailsM-CSA 165
ChainResidueDetails
AASP21metal ligand
AARG35electrostatic stabiliser, hydrogen bond donor
AASP40metal ligand
ATHR41metal ligand
AGLU43hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
AARG87electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

site_idMCSA2
Number of Residues6
DetailsM-CSA 165
ChainResidueDetails
BASP21metal ligand
BARG35electrostatic stabiliser, hydrogen bond donor
BASP40metal ligand
BTHR41metal ligand
BGLU43hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
BARG87electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

218853

PDB entries from 2024-04-24

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