1SMR

The 3-d structure of mouse submaxillary renin complexed with a decapeptide inhibitor ch-66 based on the 4-16 fragment of rat angiotensinogen

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004190	molecular_function	aspartic-type endopeptidase activity
A	0006508	biological_process	proteolysis
C	0004190	molecular_function	aspartic-type endopeptidase activity
C	0006508	biological_process	proteolysis
E	0004190	molecular_function	aspartic-type endopeptidase activity
E	0006508	biological_process	proteolysis
G	0004190	molecular_function	aspartic-type endopeptidase activity
G	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	CA2
Number of Residues	2
Details	ACTIVE SITE RESIDUES IN CHAIN C

Chain	Residue
C	ASP32
C	ASP215

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site_id	CA3
Number of Residues	2
Details	ACTIVE SITE RESIDUES IN CHAIN E

Chain	Residue
E	ASP32
E	ASP215

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site_id	CA4
Number of Residues	2
Details	ACTIVE SITE RESIDUES IN CHAIN G

Chain	Residue
G	ASP32
G	ASP215

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site_id	CAT
Number of Residues	2
Details	ACTIVE SITE RESIDUES IN CHAIN A

Chain	Residue
A	ASP32
A	ASP215

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Functional Information from PROSITE/UniProt

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIFDTGSANLWV

Chain	Residue	Details
A	VAL29-VAL40
A	VAL212-ALA223

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:1608447

Chain	Residue	Details
A	ASP32
A	ASP215
C	ASP32
C	ASP215
E	ASP32
E	ASP215
G	ASP32
G	ASP215

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