1RZ4
Crystal Structure of Human eIF3k
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001732 | biological_process | formation of cytoplasmic translation initiation complex |
| A | 0002183 | biological_process | cytoplasmic translational initiation |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005852 | cellular_component | eukaryotic translation initiation factor 3 complex |
| A | 0006412 | biological_process | translation |
| A | 0006413 | biological_process | translational initiation |
| A | 0006446 | biological_process | regulation of translational initiation |
| A | 0016020 | cellular_component | membrane |
| A | 0016282 | cellular_component | eukaryotic 43S preinitiation complex |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0033290 | cellular_component | eukaryotic 48S preinitiation complex |
| A | 0043022 | molecular_function | ribosome binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | ARG97 |
| A | GLN101 |
| A | ILE131 |
| A | THR132 |
| A | GLY133 |
| A | HOH1037 |
| A | HOH1109 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0000255|HAMAP-Rule:MF_03010, ECO:0000269|PubMed:17322308, ECO:0000269|Ref.11, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | ALA2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR28 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| A | SER217 |
