1RVG
crystal structure of class II fructose-bisphosphate aldolase from Thermus aquaticus in complex with Y
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006096 | biological_process | glycolytic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| A | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006096 | biological_process | glycolytic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006096 | biological_process | glycolytic process |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016832 | molecular_function | aldehyde-lyase activity |
| C | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006096 | biological_process | glycolytic process |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016832 | molecular_function | aldehyde-lyase activity |
| D | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1601 |
| Chain | Residue |
| A | ARG278 |
| B | SER49 |
| B | GLY51 |
| B | ARG257 |
| B | HOH1744 |
| B | HOH1926 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1602 |
| Chain | Residue |
| B | ASN251 |
| B | ASP253 |
| B | THR254 |
| B | HOH1775 |
| B | HOH1831 |
| B | HOH1884 |
| B | GLY209 |
| B | ALA210 |
| B | SER211 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1603 |
| Chain | Residue |
| A | SER49 |
| A | GLY51 |
| A | HOH1887 |
| A | HOH1978 |
| B | ARG278 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1604 |
| Chain | Residue |
| A | HIS178 |
| A | GLY179 |
| A | GLY209 |
| A | ALA210 |
| A | SER211 |
| A | ASP253 |
| A | THR254 |
| A | HOH1906 |
| A | HOH2027 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1605 |
| Chain | Residue |
| C | SER49 |
| C | GLY51 |
| C | ARG257 |
| C | HOH1771 |
| D | ARG278 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1606 |
| Chain | Residue |
| C | GLY209 |
| C | SER211 |
| C | ASN251 |
| C | ASP253 |
| C | THR254 |
| C | HOH1738 |
| C | HOH1855 |
| C | HOH1952 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1607 |
| Chain | Residue |
| C | ARG278 |
| D | SER49 |
| D | GLY51 |
| D | ARG257 |
| D | HOH1752 |
| D | HOH1753 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1608 |
| Chain | Residue |
| D | GLY209 |
| D | SER211 |
| D | ASN251 |
| D | THR252 |
| D | ASP253 |
| D | THR254 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1609 |
| Chain | Residue |
| A | SER104 |
| A | GLU132 |
| A | ARG135 |
| A | LEU136 |
| A | YT31801 |
| A | HOH2006 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1610 |
| Chain | Residue |
| B | ARG116 |
| B | HIS123 |
| B | HOH1792 |
| B | HOH1845 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1611 |
| Chain | Residue |
| C | ARG116 |
| C | HIS123 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CO B 1701 |
| Chain | Residue |
| B | HIS81 |
| B | GLU132 |
| B | HIS178 |
| B | HIS208 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NA B 1702 |
| Chain | Residue |
| B | HIS78 |
| B | ASP80 |
| B | MET100 |
| B | GLU130 |
| B | HIS208 |
| B | LYS249 |
| B | ASN251 |
| B | HOH1704 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO A 1703 |
| Chain | Residue |
| A | HIS81 |
| A | HIS178 |
| A | HIS208 |
| A | CO1709 |
| A | HOH1944 |
| A | HOH2027 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 1704 |
| Chain | Residue |
| A | HIS78 |
| A | ASP80 |
| A | MET100 |
| A | GLU130 |
| A | HIS208 |
| A | LYS249 |
| A | HOH1803 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CO C 1705 |
| Chain | Residue |
| C | HIS81 |
| C | GLU132 |
| C | HIS178 |
| C | HIS208 |
| C | HOH1715 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 1706 |
| Chain | Residue |
| C | HIS208 |
| C | LYS249 |
| C | ASN251 |
| C | HIS78 |
| C | ASP80 |
| C | GLU130 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CO D 1707 |
| Chain | Residue |
| D | HIS81 |
| D | GLU132 |
| D | HIS178 |
| D | HIS208 |
| D | HOH1729 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 1708 |
| Chain | Residue |
| D | HIS78 |
| D | ASP80 |
| D | GLU130 |
| D | HIS208 |
| D | LYS249 |
| D | ASN251 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO A 1709 |
| Chain | Residue |
| A | HIS81 |
| A | LEU136 |
| A | HIS178 |
| A | HIS208 |
| A | CO1703 |
| A | HOH1964 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE YT3 A 1801 |
| Chain | Residue |
| A | ASP102 |
| A | SER104 |
| A | GLU132 |
| A | SO41609 |
| A | HOH1964 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b57 |
| Chain | Residue | Details |
| A | ASP80 | |
| A | ASN251 | |
| A | GLU140 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b57 |
| Chain | Residue | Details |
| B | ASP80 | |
| B | ASN251 | |
| B | GLU140 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b57 |
| Chain | Residue | Details |
| C | ASP80 | |
| C | ASN251 | |
| C | GLU140 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b57 |
| Chain | Residue | Details |
| D | ASP80 | |
| D | ASN251 | |
| D | GLU140 |
