1PO3
Crystal structure of ferric citrate transporter FecA in complex with ferric citrate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0009279 | cellular_component | cell outer membrane |
| A | 0015343 | molecular_function | siderophore-iron transmembrane transporter activity |
| A | 0015891 | biological_process | siderophore transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019867 | cellular_component | outer membrane |
| A | 0023019 | biological_process | signal transduction involved in regulation of gene expression |
| A | 0033214 | biological_process | siderophore-dependent iron import into cell |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0044718 | biological_process | siderophore transmembrane transport |
| A | 1902495 | cellular_component | transmembrane transporter complex |
| A | 1990641 | biological_process | response to iron ion starvation |
| B | 0005515 | molecular_function | protein binding |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0006826 | biological_process | iron ion transport |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0009279 | cellular_component | cell outer membrane |
| B | 0015343 | molecular_function | siderophore-iron transmembrane transporter activity |
| B | 0015891 | biological_process | siderophore transport |
| B | 0016020 | cellular_component | membrane |
| B | 0019867 | cellular_component | outer membrane |
| B | 0023019 | biological_process | signal transduction involved in regulation of gene expression |
| B | 0033214 | biological_process | siderophore-dependent iron import into cell |
| B | 0038023 | molecular_function | signaling receptor activity |
| B | 0044718 | biological_process | siderophore transmembrane transport |
| B | 1902495 | cellular_component | transmembrane transporter complex |
| B | 1990641 | biological_process | response to iron ion starvation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE FLC A 742 |
| Chain | Residue |
| A | THR138 |
| A | FLC743 |
| A | FE744 |
| A | FE745 |
| A | ARG365 |
| A | GLN371 |
| A | ARG380 |
| A | ARG419 |
| A | ARG438 |
| A | GLN570 |
| A | ASP573 |
| A | ASN721 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC A 743 |
| Chain | Residue |
| A | GLN178 |
| A | SER180 |
| A | ARG365 |
| A | ARG380 |
| A | SER521 |
| A | SER568 |
| A | GLN570 |
| A | FLC742 |
| A | FE744 |
| A | FE745 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FE A 744 |
| Chain | Residue |
| A | FLC742 |
| A | FLC743 |
| A | FE745 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE A 745 |
| Chain | Residue |
| A | GLN570 |
| A | FLC742 |
| A | FLC743 |
| A | FE744 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FLC B 742 |
| Chain | Residue |
| B | THR138 |
| B | ARG365 |
| B | ARG380 |
| B | ARG438 |
| B | GLN570 |
| B | ASN721 |
| B | FLC743 |
| B | FE744 |
| B | FE745 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC B 743 |
| Chain | Residue |
| B | GLN176 |
| B | GLN178 |
| B | SER180 |
| B | ARG365 |
| B | ARG380 |
| B | SER521 |
| B | GLN570 |
| B | FLC742 |
| B | FE744 |
| B | FE745 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FE B 744 |
| Chain | Residue |
| B | FLC742 |
| B | FLC743 |
| B | FE745 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE B 745 |
| Chain | Residue |
| B | GLN570 |
| B | FLC742 |
| B | FLC743 |
| B | FE744 |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 40 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. hhhhhhhhhhaqvniapgsldkalnqyaahsg...................................................................................FTLSVDAS |
| Chain | Residue | Details |
| A | HIS-9-SER30 |
| site_id | PS01156 |
| Number of Residues | 18 |
| Details | TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. GiyaGqPRtLyMQGsLkF |
| Chain | Residue | Details |
| A | GLY724-PHE741 |
