1OC2
The structure of NADH in the dTDP-D-glucose dehydratase (RmlB) enzyme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008460 | molecular_function | dTDP-glucose 4,6-dehydratase activity |
| A | 0009225 | biological_process | nucleotide-sugar metabolic process |
| A | 0010253 | biological_process | UDP-rhamnose biosynthetic process |
| A | 0010280 | molecular_function | UDP-L-rhamnose synthase activity |
| A | 0010315 | biological_process | auxin export across the plasma membrane |
| A | 0016829 | molecular_function | lyase activity |
| A | 0050377 | molecular_function | UDP-glucose 4,6-dehydratase activity |
| A | 0051555 | biological_process | flavonol biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0008460 | molecular_function | dTDP-glucose 4,6-dehydratase activity |
| B | 0009225 | biological_process | nucleotide-sugar metabolic process |
| B | 0010253 | biological_process | UDP-rhamnose biosynthetic process |
| B | 0010280 | molecular_function | UDP-L-rhamnose synthase activity |
| B | 0010315 | biological_process | auxin export across the plasma membrane |
| B | 0016829 | molecular_function | lyase activity |
| B | 0050377 | molecular_function | UDP-glucose 4,6-dehydratase activity |
| B | 0051555 | biological_process | flavonol biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A1351 |
| Chain | Residue |
| A | LYS258 |
| A | THR309 |
| A | ASP310 |
| A | PHE311 |
| A | SER312 |
| A | HOH2394 |
| A | HOH2395 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 A1352 |
| Chain | Residue |
| A | ASP255 |
| A | ARG299 |
| A | SO41353 |
| A | HOH2320 |
| A | HOH2396 |
| A | HOH2397 |
| A | HOH2398 |
| A | HOH2399 |
| A | HOH2400 |
| A | HOH2401 |
| A | LEU52 |
| A | GLY53 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A1353 |
| Chain | Residue |
| A | GLY53 |
| A | ASP54 |
| A | ARG55 |
| A | SO41352 |
| A | HOH2062 |
| A | HOH2400 |
| A | HOH2401 |
| A | HOH2402 |
| A | HOH2403 |
| A | HOH2404 |
| site_id | AC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE TDX A1349 |
| Chain | Residue |
| A | SER86 |
| A | HIS87 |
| A | ASN88 |
| A | THR125 |
| A | GLU127 |
| A | TYR161 |
| A | ASN190 |
| A | GLU199 |
| A | LYS200 |
| A | PHE201 |
| A | ARG204 |
| A | GLN205 |
| A | LYS216 |
| A | LEU217 |
| A | TYR218 |
| A | ASN223 |
| A | ARG225 |
| A | ASN260 |
| A | ARG284 |
| A | HIS287 |
| A | TYR340 |
| A | NAD1350 |
| A | HOH2211 |
| A | HOH2212 |
| A | HOH2310 |
| A | HOH2387 |
| A | HOH2388 |
| site_id | AC5 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE NAD A1350 |
| Chain | Residue |
| A | ALA13 |
| A | GLY14 |
| A | PHE15 |
| A | ILE16 |
| A | ASP37 |
| A | LYS38 |
| A | LEU39 |
| A | THR40 |
| A | ALA42 |
| A | GLY43 |
| A | GLY61 |
| A | ASP62 |
| A | ILE63 |
| A | TYR82 |
| A | ALA83 |
| A | ALA84 |
| A | SER86 |
| A | THR101 |
| A | VAL123 |
| A | SER124 |
| A | TYR161 |
| A | LYS165 |
| A | CYS188 |
| A | SER189 |
| A | ASN190 |
| A | ASN191 |
| A | TDX1349 |
| A | HOH2051 |
| A | HOH2113 |
| A | HOH2211 |
| A | HOH2214 |
| A | HOH2220 |
| A | HOH2389 |
| A | HOH2390 |
| A | HOH2391 |
| A | HOH2392 |
| A | HOH2393 |
| site_id | AC6 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAD B1348 |
| Chain | Residue |
| B | LEU39 |
| B | THR40 |
| B | ALA42 |
| B | GLY43 |
| B | GLY61 |
| B | ASP62 |
| B | ILE63 |
| B | TYR82 |
| B | ALA83 |
| B | ALA84 |
| B | SER86 |
| B | THR101 |
| B | VAL123 |
| B | SER124 |
| B | TYR161 |
| B | LYS165 |
| B | CYS188 |
| B | SER189 |
| B | ASN191 |
| B | TDX1349 |
| B | HOH2050 |
| B | HOH2115 |
| B | HOH2218 |
| B | HOH2227 |
| B | HOH2345 |
| B | HOH2346 |
| B | HOH2347 |
| B | HOH2348 |
| B | HOH2349 |
| B | HOH2350 |
| B | ALA13 |
| B | GLY14 |
| B | PHE15 |
| B | ILE16 |
| B | ASP37 |
| B | LYS38 |
| site_id | AC7 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE TDX B1349 |
| Chain | Residue |
| B | SER86 |
| B | HIS87 |
| B | ASN88 |
| B | THR125 |
| B | GLU127 |
| B | TYR161 |
| B | ASN190 |
| B | GLU199 |
| B | LYS200 |
| B | PHE201 |
| B | ARG204 |
| B | GLN205 |
| B | LYS216 |
| B | LEU217 |
| B | TYR218 |
| B | ARG225 |
| B | ASN260 |
| B | ARG284 |
| B | HIS287 |
| B | TYR340 |
| B | NAD1348 |
| B | HOH2219 |
| B | HOH2351 |
| B | HOH2352 |
| B | HOH2353 |
