Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 701 |
| Chain | Residue |
| A | GLU42 |
| A | HIS46 |
| B | GLU166 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 702 |
| Chain | Residue |
| B | HIS23 |
| B | GLU30 |
| B | HOH830 |
| C | HIS23 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN C 703 |
| Chain | Residue |
| C | ASP65 |
| A | HIS23 |
| A | HOH791 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 704 |
| Chain | Residue |
| A | GLU166 |
| B | GLU42 |
| B | HIS46 |
| B | LEU241 |
| B | HOH721 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN C 705 |
| Chain | Residue |
| C | GLU42 |
| C | LYS45 |
| C | HIS46 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE AMQ C 601 |
| Chain | Residue |
| C | TYR61 |
| C | PRO89 |
| C | LEU90 |
| C | THR91 |
| C | ARG96 |
| C | GLY141 |
| C | SER142 |
| C | THR143 |
| C | GLU193 |
| C | MET196 |
| C | TYR220 |
| C | HOH814 |
| C | HOH815 |
| C | HOH816 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE AMQ A 602 |
| Chain | Residue |
| A | TYR61 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | LEU192 |
| A | GLU193 |
| A | MET196 |
| A | TYR220 |
| A | HOH833 |
| A | HOH835 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE AMQ B 603 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR143 |
| B | LEU192 |
| B | GLU193 |
| B | MET196 |
| B | TYR220 |
| B | HOH812 |
| B | HOH867 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR91 | |
| B | SER142 | |
| B | THR143 | |
| B | GLU193 | |
| C | PRO89 | |
| C | THR91 | |
| C | ARG96 | |
| C | SER142 | |
| C | THR143 | |
| C | GLU193 | |
| A | PRO89 | |
| A | ARG96 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 | |
| B | PRO89 | |
| B | THR91 | |
| B | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| B | ARG64 | |
| B | ARG148 | |
| B | LYS240 | |
| C | ARG64 | |
| C | ARG148 | |
| C | LYS240 | |
| A | ARG148 | |
| A | LYS240 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| B | ILE121 | |
| C | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 | |
| C | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 | |
| C | SER184 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| B | ASN3 | |
| C | ASN3 | |
