1ME5

Crystal Structure of Mycobacterium Tuberculosis Alkylperoxidase AhpD H132Q Mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006979	biological_process	response to oxidative stress
A	0008785	molecular_function	alkyl hydroperoxide reductase activity
A	0015036	molecular_function	disulfide oxidoreductase activity
A	0016209	molecular_function	antioxidant activity
A	0032843	molecular_function	hydroperoxide reductase activity
A	0045454	biological_process	cell redox homeostasis
A	0051920	molecular_function	peroxiredoxin activity
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006979	biological_process	response to oxidative stress
B	0008785	molecular_function	alkyl hydroperoxide reductase activity
B	0015036	molecular_function	disulfide oxidoreductase activity
B	0016209	molecular_function	antioxidant activity
B	0032843	molecular_function	hydroperoxide reductase activity
B	0045454	biological_process	cell redox homeostasis
B	0051920	molecular_function	peroxiredoxin activity
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006979	biological_process	response to oxidative stress
C	0008785	molecular_function	alkyl hydroperoxide reductase activity
C	0015036	molecular_function	disulfide oxidoreductase activity
C	0016209	molecular_function	antioxidant activity
C	0032843	molecular_function	hydroperoxide reductase activity
C	0045454	biological_process	cell redox homeostasis
C	0051920	molecular_function	peroxiredoxin activity
C	0098869	biological_process	cellular oxidant detoxification

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01676, ECO:0000269|PubMed:11914371

Chain	Residue	Details
A	CYS130
B	CYS130
C	CYS130

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site_id	SWS_FT_FI2
Number of Residues	3
Details	ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_01676, ECO:0000269|PubMed:11914371

Chain	Residue	Details
A	CYS133
B	CYS133
C	CYS133

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