1LY9
The impact of the physical and chemical environment on the molecular structure of Coprinus cinereus peroxidase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000302 | biological_process | response to reactive oxygen species |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0020037 | molecular_function | heme binding |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| A | 0140825 | molecular_function | lactoperoxidase activity |
| B | 0000302 | biological_process | response to reactive oxygen species |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0020037 | molecular_function | heme binding |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0140825 | molecular_function | lactoperoxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 9001 |
| Chain | Residue |
| B | SER184 |
| B | ASP201 |
| B | THR203 |
| B | VAL206 |
| B | ASP208 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 9002 |
| Chain | Residue |
| A | ASP208 |
| A | SER184 |
| A | ASP201 |
| A | THR203 |
| A | VAL206 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 9003 |
| Chain | Residue |
| A | ASP56 |
| A | GLY74 |
| A | ASP76 |
| A | SER78 |
| A | HOH1009 |
| A | HOH1027 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 9004 |
| Chain | Residue |
| B | ASP56 |
| B | GLY74 |
| B | ASP76 |
| B | SER78 |
| B | HOH2009 |
| B | HOH2027 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM A 344 |
| Chain | Residue |
| A | ARG47 |
| A | LEU50 |
| A | ARG51 |
| A | PHE54 |
| A | GLY154 |
| A | PRO155 |
| A | LEU180 |
| A | ALA182 |
| A | HIS183 |
| A | LEU185 |
| A | ALA186 |
| A | SER187 |
| A | GLU189 |
| A | GLY190 |
| A | LEU191 |
| A | MET242 |
| A | SER244 |
| A | MET276 |
| A | HOH1010 |
| A | HOH1011 |
| A | HOH1014 |
| A | HOH3054 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B 344 |
| Chain | Residue |
| A | HOH3091 |
| B | ARG47 |
| B | LEU50 |
| B | ARG51 |
| B | PHE54 |
| B | GLY154 |
| B | PRO155 |
| B | LEU179 |
| B | LEU180 |
| B | ALA182 |
| B | HIS183 |
| B | LEU185 |
| B | ALA186 |
| B | SER187 |
| B | GLU189 |
| B | GLY190 |
| B | LEU191 |
| B | MET242 |
| B | SER244 |
| B | MET276 |
| B | HOH2010 |
| B | HOH2011 |
| B | HOH2014 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | HIS55 | |
| B | HIS55 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP56 | |
| B | ASP56 | |
| B | GLY74 | |
| B | ASP76 | |
| B | SER78 | |
| B | SER184 | |
| B | ASP201 | |
| B | THR203 | |
| B | VAL206 | |
| B | ASP208 | |
| A | GLY74 | |
| A | ASP76 | |
| A | SER78 | |
| A | SER184 | |
| A | ASP201 | |
| A | THR203 | |
| A | VAL206 | |
| A | ASP208 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | HIS183 | |
| B | HIS183 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer |
| Chain | Residue | Details |
| A | ARG51 | |
| B | ARG51 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:8477731 |
| Chain | Residue | Details |
| A | GLN1 | |
| B | GLN1 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine => ECO:0000269|PubMed:8112469 |
| Chain | Residue | Details |
| A | SER142 | |
| B | SER142 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CARBOHYD: O-linked (Man...) serine => ECO:0000269|PubMed:8112469 |
| Chain | Residue | Details |
| A | ALA338 | |
| B | ALA338 |
