1KD6

Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006811	biological_process	monoatomic ion transport
A	0006812	biological_process	monoatomic cation transport
A	0015267	molecular_function	channel activity
A	0016020	cellular_component	membrane
A	0031640	biological_process	killing of cells of another organism
A	0035821	biological_process	modulation of process of another organism
A	0042151	cellular_component	nematocyst
A	0044218	cellular_component	other organism cell membrane
A	0046930	cellular_component	pore complex
A	0046931	biological_process	pore complex assembly
A	0051715	biological_process	cytolysis in another organism
A	0055085	biological_process	transmembrane transport
A	0090729	molecular_function	toxin activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P07845

Chain	Residue	Details
A	SER54
A	VAL87
A	SER105
A	PRO107
A	TYR133
A	TYR137
A	TYR138

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Important in the initial contact with the lipid membrane => ECO:0000269|PubMed:18442982

Chain	Residue	Details
A	TRP112
A	TYR113

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Interacts with the lipid membrane => ECO:0000269|PubMed:18442982

Chain	Residue	Details
A	ARG144
A	SER160

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