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1KCX

X-ray structure of NYSGRC target T-45

Functional Information from GO Data
ChainGOidnamespacecontents
A0004157molecular_functiondihydropyrimidinase activity
A0005737cellular_componentcytoplasm
A0005813cellular_componentcentrosome
A0005819cellular_componentspindle
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0006208biological_processpyrimidine nucleobase catabolic process
A0015629cellular_componentactin cytoskeleton
A0016787molecular_functionhydrolase activity
A0016810molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A0016812molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0030425cellular_componentdendrite
A0030426cellular_componentgrowth cone
A0042995cellular_componentcell projection
A0043025cellular_componentneuronal cell body
A0043204cellular_componentperikaryon
A0051219molecular_functionphosphoprotein binding
A0071526biological_processsemaphorin-plexin signaling pathway
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A0150052biological_processregulation of postsynapse assembly
B0004157molecular_functiondihydropyrimidinase activity
B0005737cellular_componentcytoplasm
B0005813cellular_componentcentrosome
B0005819cellular_componentspindle
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0006208biological_processpyrimidine nucleobase catabolic process
B0015629cellular_componentactin cytoskeleton
B0016787molecular_functionhydrolase activity
B0016810molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B0016812molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B0030425cellular_componentdendrite
B0030426cellular_componentgrowth cone
B0042995cellular_componentcell projection
B0043025cellular_componentneuronal cell body
B0043204cellular_componentperikaryon
B0051219molecular_functionphosphoprotein binding
B0071526biological_processsemaphorin-plexin signaling pathway
B0098793cellular_componentpresynapse
B0098794cellular_componentpostsynapse
B0150052biological_processregulation of postsynapse assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q62950
ChainResidueDetails
ASER8
ASER521
ASER522
BSER8
BSER521
BSER522

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: Phosphothreonine; by AURKA => ECO:0000250|UniProtKB:Q14194
ChainResidueDetails
ATHR101
ATHR102
BTHR101
BTHR102

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: 3'-nitrotyrosine => ECO:0007744|PubMed:16800626
ChainResidueDetails
ATYR316
BTYR316

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18034455
ChainResidueDetails
ATYR504
BTYR504

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:15345747, ECO:0007744|PubMed:18034455, ECO:0007744|PubMed:21183079
ChainResidueDetails
ATHR509
BTHR509

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PDB entries from 2024-05-15

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