Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004063 | molecular_function | aryldialkylphosphatase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009056 | biological_process | catabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004063 | molecular_function | aryldialkylphosphatase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009056 | biological_process | catabolic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD A 1 |
| Chain | Residue |
| A | EDO8 |
| A | HIS55 |
| A | HIS57 |
| A | KCX169 |
| A | ASP301 |
| A | HOH590 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD A 2 |
| Chain | Residue |
| A | HOH590 |
| A | HOH646 |
| A | HOH699 |
| A | KCX169 |
| A | HIS201 |
| A | HIS230 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 3 |
| Chain | Residue |
| B | EDO7 |
| B | HIS55 |
| B | HIS57 |
| B | KCX169 |
| B | ASP301 |
| B | HOH721 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 4 |
| Chain | Residue |
| B | KCX169 |
| B | HIS201 |
| B | HIS230 |
| B | HOH606 |
| B | HOH681 |
| B | HOH721 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 5 |
| Chain | Residue |
| A | ASN38 |
| A | ILE154 |
| A | HOH371 |
| A | HOH376 |
| A | HOH557 |
| A | HOH615 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 6 |
| Chain | Residue |
| B | ASN38 |
| B | ILE154 |
| B | HOH391 |
| B | HOH559 |
| B | HOH566 |
| B | HOH593 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO B 7 |
| Chain | Residue |
| B | CD3 |
| B | EDO20 |
| B | HIS57 |
| B | TRP131 |
| B | KCX169 |
| B | PHE306 |
| B | SER308 |
| B | EDO368 |
| B | HOH606 |
| B | HOH721 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 8 |
| Chain | Residue |
| A | CD1 |
| A | EDO22 |
| A | HIS57 |
| A | TRP131 |
| A | KCX169 |
| A | PHE306 |
| A | HOH648 |
| A | HOH699 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 9 |
| Chain | Residue |
| A | ARG91 |
| B | ARG189 |
| B | HOH481 |
| B | HOH567 |
| B | HOH700 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 10 |
| Chain | Residue |
| A | HOH469 |
| A | HOH568 |
| A | HOH577 |
| A | HOH602 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 11 |
| Chain | Residue |
| A | VAL84 |
| A | GLU115 |
| A | ALA119 |
| A | HOH430 |
| A | HOH595 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 12 |
| Chain | Residue |
| A | EDO13 |
| A | THR147 |
| A | ARG189 |
| A | HOH487 |
| A | HOH554 |
| A | HOH607 |
| B | ARG91 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 13 |
| Chain | Residue |
| A | EDO12 |
| A | HOH607 |
| B | ARG91 |
| B | ASP121 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 14 |
| Chain | Residue |
| B | EDO24 |
| B | ARG76 |
| B | LYS77 |
| B | GLU115 |
| B | HOH424 |
| B | HOH610 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 15 |
| Chain | Residue |
| B | GLY305 |
| B | PHE306 |
| B | MET314 |
| B | HOH540 |
| B | HOH723 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 16 |
| Chain | Residue |
| B | PRO256 |
| B | VAL320 |
| B | PHE327 |
| B | HOH575 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 17 |
| Chain | Residue |
| B | PRO135 |
| B | HOH370 |
| B | HOH372 |
| A | ASP133 |
| A | PRO135 |
| A | HOH712 |
| B | ASP133 |
| B | PRO134 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 18 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 19 |
| Chain | Residue |
| A | PRO256 |
| A | TRP277 |
| A | VAL320 |
| A | PHE327 |
| A | HOH591 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 20 |
| Chain | Residue |
| B | EDO7 |
| B | HIS257 |
| B | ASP301 |
| B | HOH721 |
| B | HOH742 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 21 |
| Chain | Residue |
| A | ARG41 |
| A | PRO43 |
| B | GLU338 |
| B | HOH580 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 22 |
| Chain | Residue |
| A | EDO8 |
| A | PHE306 |
| A | SER308 |
| A | HOH597 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 23 |
| Chain | Residue |
| A | SER224 |
| A | ARG225 |
| A | LEU249 |
| A | ARG356 |
| A | PHE357 |
| A | HOH609 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 24 |
| Chain | Residue |
| B | EDO14 |
| B | ALA80 |
| B | GLU81 |
| B | GLU115 |
| B | HOH648 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 25 |
| Chain | Residue |
| A | ALA266 |
| A | SER269 |
| A | ALA270 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 26 |
| Chain | Residue |
| A | HOH586 |
| A | HOH671 |
| B | TYR156 |
| B | HOH466 |
| B | HOH656 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 27 |
| Chain | Residue |
| A | PHE73 |
| A | GLY74 |
| A | ALA78 |
| A | HOH589 |
| A | HOH629 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 28 |
| Chain | Residue |
| A | LYS285 |
| A | ILE288 |
| A | ASP289 |
| A | VAL341 |
| A | PRO342 |
| A | HOH523 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 29 |
| Chain | Residue |
| A | GLY305 |
| A | PHE306 |
| A | MET314 |
| A | HOH422 |
| A | HOH526 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 366 |
| Chain | Residue |
| A | ARG152 |
| A | TYR156 |
| B | GLU71 |
| B | HOH377 |
| B | HOH658 |
| site_id | DC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 367 |
| Chain | Residue |
| A | ILE333 |
| A | ARG337 |
| A | GLN343 |
| A | HOH394 |
| B | TYR156 |
| B | HOH469 |
| B | HOH674 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 366 |
| Chain | Residue |
| A | THR173 |
| A | HOH605 |
| site_id | DC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 368 |
| Chain | Residue |
| B | EDO7 |
| B | SER308 |
| B | TYR309 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEL B 369 |
| Chain | Residue |
| B | LYS77 |
| B | MET293 |
| B | GLY348 |
| B | ASN353 |
| site_id | DC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEL A 367 |
| Chain | Residue |
| A | LYS77 |
| A | MET293 |
| A | THR345 |
| A | GLY348 |
| A | ILE349 |
| A | ASN353 |
| site_id | DC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEL A 368 |
| Chain | Residue |
| A | ARG88 |
| A | ARG89 |
| A | HOH580 |
| B | LEU362 |
| B | ARG363 |
Functional Information from PROSITE/UniProt
| site_id | PS01322 |
| Number of Residues | 9 |
| Details | PHOSPHOTRIESTERASE_1 Phosphotriesterase family signature 1. GfTLtHEHI |
| Chain | Residue | Details |
| A | GLY50-ILE58 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS55 | |
| B | ASP301 | |
| A | HIS57 | |
| A | HIS201 | |
| A | HIS230 | |
| A | ASP301 | |
| B | HIS55 | |
| B | HIS57 | |
| B | HIS201 | |
| B | HIS230 | |
| Chain | Residue | Details |
| A | KCX169 | |
| B | KCX169 | |
| Chain | Residue | Details |
| A | KCX169 | |
| B | KCX169 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 8 |
| Details | M-CSA 159 |
| Chain | Residue | Details |
| A | HIS55 | metal ligand |
| A | HIS57 | metal ligand |
| A | KCX169 | metal ligand |
| A | HIS201 | metal ligand |
| A | HIS230 | metal ligand |
| A | ASP233 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | HIS254 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| A | ASP301 | hydrogen bond acceptor, hydrogen bond donor, metal ligand, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 8 |
| Details | M-CSA 159 |
| Chain | Residue | Details |
| B | HIS55 | metal ligand |
| B | HIS57 | metal ligand |
| B | KCX169 | metal ligand |
| B | HIS201 | metal ligand |
| B | HIS230 | metal ligand |
| B | ASP233 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | HIS254 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| B | ASP301 | hydrogen bond acceptor, hydrogen bond donor, metal ligand, proton acceptor, proton donor |
