1I29
CRYSTAL STRUCTURE OF CSDB COMPLEXED WITH L-PROPARGYLGLYCINE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001887 | biological_process | selenium compound metabolic process |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006534 | biological_process | cysteine metabolic process |
| A | 0006790 | biological_process | sulfur compound metabolic process |
| A | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| A | 0009000 | molecular_function | selenocysteine lyase activity |
| A | 0016226 | biological_process | iron-sulfur cluster assembly |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0031071 | molecular_function | cysteine desulfurase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE LPG A 460 |
| Chain | Residue |
| A | ALA30 |
| A | ALA31 |
| A | HIS123 |
| A | ASN175 |
| A | ARG379 |
| A | PLP500 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PLP A 500 |
| Chain | Residue |
| A | ASP200 |
| A | ALA202 |
| A | SER223 |
| A | HIS225 |
| A | LYS226 |
| A | THR278 |
| A | LPG460 |
| A | THR94 |
| A | THR95 |
| A | ASN175 |
Functional Information from PROSITE/UniProt
| site_id | PS00595 |
| Number of Residues | 20 |
| Details | AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. CDFYvfSGHKlygpt.GiGiL |
| Chain | Residue | Details |
| A | CYS217-LEU236 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Cysteine persulfide intermediate |
| Chain | Residue | Details |
| A | CYS364 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine |
| Chain | Residue | Details |
| A | LYS226 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 855 |
| Chain | Residue | Details |
| A | HIS123 | increase basicity, proton acceptor, proton donor |
| A | ASP200 | electrostatic stabiliser, polar interaction |
| A | GLN203 | electrostatic stabiliser, polar interaction |
| A | LYS226 | covalently attached, electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | CYS364 | covalently attached, nucleophile, proton donor |
