Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0030141 | cellular_component | secretory granule |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 1250 |
| Chain | Residue |
| A | HIS48 |
| A | LYS239 |
| A | HOH2300 |
| A | HOH2301 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1251 |
| Chain | Residue |
| A | HIS184 |
| A | ASN224 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1247 |
| Chain | Residue |
| A | PHE179 |
| A | HIS234 |
| A | TRP237 |
| A | HOH2293 |
| A | HOH2294 |
| A | HOH2295 |
| A | ASP91 |
| A | GLN93 |
| A | HIS101 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1248 |
| Chain | Residue |
| A | TRP29 |
| A | ILE200 |
| A | ASP202 |
| A | GLY203 |
| A | HOH2296 |
| A | HOH2297 |
| A | HOH2298 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1249 |
| Chain | Residue |
| A | TYR34 |
| A | ARG70 |
| A | HOH2044 |
| A | HOH2299 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SIclGDSGGALI |
| Chain | Residue | Details |
| A | SER189-ILE200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN72 | |
