Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1FZ6

METHANE MONOOXYGENASE HYDROXYLASE, FORM II SOAKED IN 1 M METHANOL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005515	molecular_function	protein binding
A	0006725	biological_process	obsolete cellular aromatic compound metabolic process
A	0006730	biological_process	one-carbon metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0106317	molecular_function	methane monooxygenase NADH activity
A	0106318	molecular_function	methane monooxygenase NADPH activity
B	0004497	molecular_function	monooxygenase activity
B	0005515	molecular_function	protein binding
B	0006725	biological_process	obsolete cellular aromatic compound metabolic process
B	0006730	biological_process	one-carbon metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0106317	molecular_function	methane monooxygenase NADH activity
B	0106318	molecular_function	methane monooxygenase NADPH activity
C	0004497	molecular_function	monooxygenase activity
C	0005515	molecular_function	protein binding
C	0006725	biological_process	obsolete cellular aromatic compound metabolic process
C	0006730	biological_process	one-carbon metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
C	0106317	molecular_function	methane monooxygenase NADH activity
C	0106318	molecular_function	methane monooxygenase NADPH activity
D	0004497	molecular_function	monooxygenase activity
D	0005515	molecular_function	protein binding
D	0006725	biological_process	obsolete cellular aromatic compound metabolic process
D	0006730	biological_process	one-carbon metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
D	0106317	molecular_function	methane monooxygenase NADH activity
D	0106318	molecular_function	methane monooxygenase NADPH activity
E	0004497	molecular_function	monooxygenase activity
E	0006730	biological_process	one-carbon metabolic process
E	0015049	molecular_function	methane monooxygenase activity
E	0015947	biological_process	methane metabolic process
E	0106317	molecular_function	methane monooxygenase NADH activity
E	0106318	molecular_function	methane monooxygenase NADPH activity
F	0004497	molecular_function	monooxygenase activity
F	0006730	biological_process	one-carbon metabolic process
F	0015049	molecular_function	methane monooxygenase activity
F	0015947	biological_process	methane metabolic process
F	0106317	molecular_function	methane monooxygenase NADH activity
F	0106318	molecular_function	methane monooxygenase NADPH activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 5001

Chain	Residue
A	GLU114
A	GLU144
A	HIS147
A	FE5002
A	HOH5217
A	HOH5218
A	HOH5219

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 5002

Chain	Residue
A	GLU243
A	HIS246
A	FE5001
A	HOH5218
A	HOH5219
A	GLU144
A	GLU209

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE B 5003

Chain	Residue
B	GLU114
B	GLU144
B	HIS147
B	FE5004
B	MOH9001
B	HOH9197
B	HOH9198

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE B 5004

Chain	Residue
B	GLU144
B	GLU209
B	GLU243
B	HIS246
B	FE5003
B	MOH9001
B	HOH9198

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 5005

Chain	Residue
B	ASP334
B	GLN337
B	ASP338
B	HOH9138
B	HOH9195
B	HOH9204

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 5006

Chain	Residue
A	ASN527
A	HOH5161
A	HOH5214
A	HOH5215
A	HOH5216
A	HOH5221
B	SER428

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 5007

Chain	Residue
C	ASP348
C	HOH5239
C	HOH5240
C	HOH5253
C	HOH5254
C	HOH5255

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MOH B 9001

Chain	Residue
B	GLU114
B	GLU144
B	GLU209
B	GLU243
B	FE5003
B	FE5004
B	HOH9197
B	HOH9198

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255

Chain	Residue	Details
A	CYS151
B	CYS151

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
B	GLU114
B	GLU144
B	HIS147
B	GLU209
B	GLU243
B	HIS246
A	GLU114
A	GLU144
A	HIS147
A	GLU209
A	GLU243
A	HIS246

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)