1F2I

COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 1201

Chain	Residue
G	CYS1107
G	CYS1112
G	HIS1125
G	HIS1129

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 1202

Chain	Residue
G	CYS1137
G	CYS1140
G	HIS1153
G	HIS1157

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 2201

Chain	Residue
H	CYS2112
H	HIS2125
H	HIS2129
H	CYS2107

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 2202

Chain	Residue
H	CYS2137
H	CYS2140
H	HIS2153
H	HIS2157

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 3201

Chain	Residue
I	CYS3107
I	CYS3112
I	HIS3125
I	HIS3129

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 3202

Chain	Residue
I	CYS3137
I	CYS3140
I	HIS3153
I	HIS3157

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 4201

Chain	Residue
J	CYS4107
J	CYS4112
J	HIS4125
J	HIS4129

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 4202

Chain	Residue
J	CYS4137
J	CYS4140
J	HIS4153
J	HIS4157

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN K 5201

Chain	Residue
K	CYS5107
K	CYS5112
K	HIS5125
K	HIS5129

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN K 5202

Chain	Residue
K	CYS5137
K	CYS5140
K	HIS5153
K	HIS5157

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 6201

Chain	Residue
L	CYS6107
L	CYS6112
L	HIS6125
L	HIS6129

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 6202

Chain	Residue
L	CYS6137
L	CYS6140
L	HIS6153
L	HIS6157

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CpvesCdrrFsrsdeltrHiri..H

Chain	Residue	Details
G	CYS1107-HIS1129
G	CYS1137-HIS1157

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	144
Details	ZN_FING: C2H2-type 1 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
G	TYR1105-HIS1129
H	TYR2105-HIS2129
I	TYR3105-HIS3129
J	TYR4105-HIS4129
K	TYR5105-HIS5129
L	TYR6105-HIS6129

---

site_id	SWS_FT_FI2
Number of Residues	132
Details	ZN_FING: C2H2-type 2 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
G	PHE1135-HIS1157
H	PHE2135-HIS2157
I	PHE3135-HIS3157
J	PHE4135-HIS4157
K	PHE5135-HIS5157
L	PHE6135-HIS6157

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	SITE: Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA

Chain	Residue	Details
G	ARG1103
H	ARG2124
H	ARG2142
H	ARG2146
I	ARG3103
I	ARG3114
I	ARG3118
I	ARG3124
I	ARG3142
I	ARG3146
J	ARG4103
G	ARG1114
J	ARG4114
J	ARG4118
J	ARG4124
J	ARG4142
J	ARG4146
K	ARG5103
K	ARG5114
K	ARG5118
K	ARG5124
K	ARG5142
G	ARG1118
K	ARG5146
L	ARG6103
L	ARG6114
L	ARG6118
L	ARG6124
L	ARG6142
L	ARG6146
G	ARG1124
G	ARG1142
G	ARG1146
H	ARG2103
H	ARG2114
H	ARG2118

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