Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009039 | molecular_function | urease activity |
| A | 0016151 | molecular_function | nickel cation binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019627 | biological_process | urea metabolic process |
| A | 0035550 | cellular_component | urease complex |
| A | 0043419 | biological_process | urea catabolic process |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006807 | biological_process | obsolete nitrogen compound metabolic process |
| B | 0009039 | molecular_function | urease activity |
| B | 0016151 | molecular_function | nickel cation binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0019627 | biological_process | urea metabolic process |
| B | 0043419 | biological_process | urea catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NI B 3001 |
| Chain | Residue |
| B | KCX219 |
| B | HIS221 |
| B | HIS248 |
| B | HIS274 |
| B | ASP362 |
| B | HOH2027 |
| B | NI3002 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI B 3002 |
| Chain | Residue |
| B | KCX219 |
| B | ASP362 |
| B | NI3001 |
| B | HIS136 |
| B | HIS138 |
Functional Information from PROSITE/UniProt
| site_id | PS00145 |
| Number of Residues | 17 |
| Details | UREASE_2 Urease active site. MVCHHLdksIkeDVqFA |
| Chain | Residue | Details |
| B | MET319-ALA335 | |
| site_id | PS01120 |
| Number of Residues | 14 |
| Details | UREASE_1 Urease nickel ligands signature. TAGGIDtHIHfisP |
| Chain | Residue | Details |
| B | THR129-PRO142 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| B | HIS322 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | HIS136 | |
| B | HIS138 | |
| B | HIS248 | |
| B | HIS274 | |
| B | ASP362 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: via carbamate group |
| Chain | Residue | Details |
| B | KCX219 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| B | HIS221 | |
| Chain | Residue | Details |
| B | KCX219 | |
