1D6V

CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0003823	molecular_function	antigen binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005886	cellular_component	plasma membrane
L	0006955	biological_process	immune response
L	0016020	cellular_component	membrane
L	0016064	biological_process	immunoglobulin mediated immune response
L	0019814	cellular_component	immunoglobulin complex
L	0050853	biological_process	B cell receptor signaling pathway
L	0070062	cellular_component	extracellular exosome
L	0071735	cellular_component	IgG immunoglobulin complex
L	0071738	cellular_component	IgD immunoglobulin complex
L	0071742	cellular_component	IgE immunoglobulin complex
L	0071745	cellular_component	IgA immunoglobulin complex
L	0071753	cellular_component	IgM immunoglobulin complex
L	0072562	cellular_component	blood microparticle

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD L 501

Chain	Residue
L	GLU79
L	HOH554

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD L 502

Chain	Residue
H	HIS164
L	ASN138
L	HOH556

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD L 503

Chain	Residue
L	LYS45
L	HOH507
L	HOH568

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD L 504

Chain	Residue
L	HOH517
L	HOH566
L	GLU81

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE HOP H 401

Chain	Residue
H	GLU35
H	HIS96
H	TYR100
H	ASP101
H	TRP103
L	LEU89
L	TYR91

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR194-HIS200

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