Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| A | 0016849 | molecular_function | phosphorus-oxygen lyase activity |
| A | 0035556 | biological_process | intracellular signal transduction |
| B | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| B | 0016849 | molecular_function | phosphorus-oxygen lyase activity |
| B | 0035556 | biological_process | intracellular signal transduction |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005525 | molecular_function | GTP binding |
| C | 0007165 | biological_process | signal transduction |
| C | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| C | 0019001 | molecular_function | guanyl nucleotide binding |
| C | 0031683 | molecular_function | G-protein beta/gamma-subunit complex binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 403 |
| Chain | Residue |
| C | SER54 |
| C | THR204 |
| C | GSP405 |
| C | HOH412 |
| C | HOH415 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 404 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 581 |
| Chain | Residue |
| A | ASP440 |
| A | MN582 |
| A | HOH57 |
| A | DAD102 |
| A | ASP396 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 582 |
| Chain | Residue |
| A | DAD102 |
| A | ASP396 |
| A | ILE397 |
| A | ASP440 |
| A | MG581 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE GSP C 405 |
| Chain | Residue |
| C | GLY49 |
| C | GLU50 |
| C | SER51 |
| C | GLY52 |
| C | LYS53 |
| C | SER54 |
| C | THR55 |
| C | ASP173 |
| C | LEU198 |
| C | ARG199 |
| C | ARG201 |
| C | LEU203 |
| C | THR204 |
| C | GLY226 |
| C | ASN292 |
| C | LYS293 |
| C | ASP295 |
| C | LEU296 |
| C | CYS365 |
| C | ALA366 |
| C | MG403 |
| C | HOH412 |
| C | HOH415 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE FOK A 101 |
| Chain | Residue |
| A | HOH17 |
| A | PHE394 |
| A | TYR443 |
| A | VAL506 |
| A | TRP507 |
| A | SER508 |
| A | VAL511 |
| A | THR512 |
| A | ASN515 |
| B | PHE895 |
| B | ILE940 |
| B | GLY941 |
| B | SER942 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE DAD A 102 |
| Chain | Residue |
| A | ASP396 |
| A | ILE397 |
| A | GLU398 |
| A | GLY399 |
| A | PHE400 |
| A | THR401 |
| A | LEU438 |
| A | GLY439 |
| A | ASP440 |
| A | ARG484 |
| A | MG581 |
| A | MN582 |
| B | HOH71 |
| B | LYS938 |
| B | ASP1018 |
| B | ILE1019 |
| B | VAL1024 |
| B | ASN1025 |
| B | SER1028 |
| B | ARG1029 |
| B | LYS1065 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MES A 103 |
| Chain | Residue |
| A | ALA552 |
| A | TYR553 |
| A | GLU556 |
| B | LYS1067 |
| B | GLY1068 |
| B | ASP1069 |
| B | LEU1070 |
Functional Information from PROSITE/UniProt
| site_id | PS00452 |
| Number of Residues | 24 |
| Details | GUANYLATE_CYCLASE_1 Guanylate cyclase signature. GVI.GaqkpqYdIWGNTVNvasrmD |
| Chain | Residue | Details |
| B | GLY1008-ASP1031 | |
| A | GLY495-GLU518 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| C | GLY47 | |
| C | LEU198 | |
| C | VAL224 | |
| C | LYS293 | |
| C | VAL367 | |
| Chain | Residue | Details |
| C | SER54 | |
| C | SER205 | |
| A | GLY521 | |
| Chain | Residue | Details |
| C | GLY353 | |
| A | LEU565 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P63092 |
| Chain | Residue | Details |
| C | VAL301 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ab8 |
| Chain | Residue | Details |
| B | ARG1029 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ab8 |
| Chain | Residue | Details |
| A | HIS516 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ab8 |
| Chain | Residue | Details |
| C | THR204 | |
| C | ARG201 | |
| C | GLU50 | |
| C | GLN227 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ab8 |
| Chain | Residue | Details |
| C | GLN227 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 58 |
| Chain | Residue | Details |
| B | ARG1029 | electrostatic stabiliser |
| B | LYS1065 | electrostatic stabiliser |
| A | GLY521 | metal ligand |
